Evidence map›Paper›PMID 35620320›Full record

ArticleInternational journal of hypertension2022

Combination of

Xin Li, Li Wang, Shaojun Ma, Shaohui Lin, Chunyan Wang, Haiya Wang

Open access · goldAbstract read
In one paragraph

Article in International journal of hypertension, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Xin LiDepartment of General Medicine and Geriatrics, The Second Affiliated Hospital of School of Medicine, Linping Campus, Zhejiang University, No. 369, Yingbin Rd, Nanyuan St, Linping District, Hangzhou, Zhejiang Province 311100, China.
Li WangDepartment of Geriatrics, Renji Hospital, School of Medicine, Shanghai Jiaotong University, No. 145, Shandong Rd., Shanghai 200001, China.
Shaojun MaDepartment of Geriatrics, Shanghai Ninth People's Hospital, School of Medicine, Shanghai Jiaotong University, No. 639, Zhizaoju Rd., Shanghai 200011, China.
Shaohui LinDepartment of Geriatrics, Shanghai Ninth People's Hospital, School of Medicine, Shanghai Jiaotong University, No. 639, Zhizaoju Rd., Shanghai 200011, China.
Chunyan WangShanghai Aikesuo Biomedical Technology L.L.C, Shanghai, China.ORCID https://orcid.org/0000-0003-2428-8494
Haiya WangDepartment of Geriatrics, Shanghai Ninth People's Hospital, School of Medicine, Shanghai Jiaotong University, No. 639, Zhizaoju Rd., Shanghai 200011, China.ORCID https://orcid.org/0000-0003-2796-4902
Shanghai Ninth People's Hospital · CNRenji Hospital · CNSecond Affiliated Hospital of Zhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The human microbiome is a mixed group of microorganisms, which individually consists of 10-100 trillion symbiotic microbial cells. The relationship between gastrointestinal microbiota and blood pressure has been verified and the intestinal microbiota of chronic kidney disease (CKD) patients in the distribution of bacterial species is different from the flora of people with no CKD. The purpose of this research is to study the different intestinal microbiota of hypertensive patients with and without nephropathy and to find possible biomarkers of hypertensive nephropathy (H-CKD). The subjects of this research were divided into three groups, healthy control group, hypertension group, and hypertensive nephropathy group. Sequencing, bioinformatics, and statistical analysis were performed on the 16S rRNA gene of the subjects' stool samples. This research study showed the differences of intestinal flora as biomarkers in hypertension patients with and without nephropathy; it investigated the relationship of the differences in the intestinal microbiota with bile-acid metabolism; it also explored bile-acid metabolism mechanism of intestinal microbiota differences in hypertension with or without nephropathy. In summary, the difference in the combination of

Identifiers

PMID35620320
PMCPMC9129936
OpenAlexW4280562273

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.