Evidence map›Paper›PMID 35620209›Full record

ArticleMolecular and clinical oncology2022

Retrospective analysis of prognosis using the Gynecology Oncology Group score of stage IB-IIA node negative uterine cervical cancer after radical hysterectomy and trachelectomy.

Yasuyuki Kinjo, Yusuke Matsuura, Takayuki Ohguri, Yoko Aoyama, Midori Murakami, Kaori Hoshino, Hiroshi Harada, Taeko Ueda, Tomoko Kurita, Seiji Kagami and 1 more

Abstract read
In one paragraph

Article in Molecular and clinical oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yasuyuki KinjoDepartment of Obstetrics and Gynecology, University of Occupational and Environmental Health, Fukuoka 807-8555, Japan.
Yusuke MatsuuraDepartment of Nursing of Human Broad Development, University of Occupational and Environmental Health, Fukuoka 807-8555, Japan.
Takayuki OhguriDepartment of Radiology, University of Occupational and Environmental Health, Fukuoka 807-8555, Japan.
Yoko AoyamaDepartment of Obstetrics and Gynecology, University of Occupational and Environmental Health, Fukuoka 807-8555, Japan.
Midori MurakamiDepartment of Obstetrics and Gynecology, University of Occupational and Environmental Health, Fukuoka 807-8555, Japan.
Kaori HoshinoDepartment of Obstetrics and Gynecology, University of Occupational and Environmental Health, Fukuoka 807-8555, Japan.
Hiroshi HaradaDepartment of Obstetrics and Gynecology, University of Occupational and Environmental Health, Fukuoka 807-8555, Japan.
Taeko UedaDepartment of Obstetrics and Gynecology, University of Occupational and Environmental Health, Fukuoka 807-8555, Japan.
Tomoko KuritaDepartment of Obstetrics and Gynecology, University of Occupational and Environmental Health, Fukuoka 807-8555, Japan.
Seiji KagamiDepartment of Obstetrics and Gynecology, University of Occupational and Environmental Health, Fukuoka 807-8555, Japan.
Kiyoshi YoshinoDepartment of Obstetrics and Gynecology, University of Occupational and Environmental Health, Fukuoka 807-8555, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is currently controversy regarding the criteria for low and intermediate risk of cervical cancer (CC) after surgery. In the present study, the Gynecology Oncology Group (GOG) score was used to detect intermediate risk. Adjuvant radiotherapy was applied in the case of a GOG score >120. The present study aimed to evaluate the validity of the recurrence risk classification using the GOG score for stage IB-IIA node-negative CC. All cases of stage IB-IIA node-negative CC who underwent radical surgery between February 2007 and December 2015 were retrospectively reviewed. The GOG scores were determined from clinical and pathological findings and accordingly, subjects were divided into 4 groups: A, ≤40; B, >40 and ≤70; C, >70 and ≤120; and D, >120. Overall survival (OS) and recurrence-free survival (RFS) curves were generated using the Kaplan-Meier method. The log-rank test produced an estimated P-value by comparing the OS and RFS of group A (low-score group) with those of others. The present study included 61 patients (mean age, 47.82 years; age range, 22-76 years) and the median follow-up was 79 (39-149) months. Of these, 60 patients were observed for at least 60 months. During the follow-up period, the OS and RFS rates of group C were 94.7 and 84.2%, respectively, while those of group D were 100 and 91.7%, respectively; the OS and RFS of groups A and B were 100%. Log-rank tests for all OS and RFS indicated no significant differences compared to group A. It was indicated that a GOG score ≤70 does not require adjuvant therapy; however, a GOG score >70 requires consideration of adjuvant therapy based on the risk factors which constitute the score.

Indexed as

adjuvant radiotherapyhysterectomypostoperative caretreatment outcomeuterine cervical neoplasms

Identifiers

PMID35620209
PMCPMC9112379

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.