Evidence map›Paper›PMID 35620203›Full record

Trial reportComputational and mathematical methods in medicine2022

Effect of Ultrasound-Guided Fascia Iliac Compartment Block on Serum NLRP3 and Inflammatory Factors in Patients with Femoral Intertrochanteric Fracture.

Kailai Zhu, Fang Zheng, Chuanguang Wang, Leiming Ding

Registry-linked trialOpen access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Computational and mathematical methods in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06636331 (Comparison of The Continous Suprainguinal Fascia Iliaca Compartment Block and Continous Epidual on The Quality of Postoperative Analgesia, Interleukin-6, Hemodynamic Stability and QoR-40 for Cephalomedullary Nailing Surgeries), which is not on this map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06636331 naenrolling by invitationnot on this mapstarted 2024, after this paper: background citation

Comparison of The Continous Suprainguinal Fascia Iliaca Compartment Block and Continous Epidual on The Quality of Postoperative Analgesia, Interleukin-6, Hemodynamic Stability and QoR-40 for Cephalomedullary Nailing Surgeries

TypeinterventionalSponsorUdayana UniversityRan2024 to 2024Enrolled46ConditionsPain, PostoperativeArmsContinuous Suprainguinal Fascia Iliaca Compartment Block, Continuous Epidural
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. [Observation on analgesic efficacy of ultrasound-guided high fascia iliac compartment block for tourniquet-related pain following total knee arthroplasty].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2025
    Trial
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Kailai ZhuDepartment of Anesthesiology, Lishui Municipal Central Hospital, Lishui, Zhejiang 323000, China.
Fang ZhengDepartment of Anesthesiology, Lishui Municipal Central Hospital, Lishui, Zhejiang 323000, China.
Chuanguang WangDepartment of Anesthesiology, Lishui Municipal Central Hospital, Lishui, Zhejiang 323000, China.
Leiming DingDepartment of Anesthesiology, Lishui Municipal Central Hospital, Lishui, Zhejiang 323000, China.ORCID https://orcid.org/0000-0002-0947-4216
Lishui Central Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To investigate the effects of ultrasound-guided fascia iliac compartment block (FICB) on patients' postoperative pain and inflammatory factors as well as nucleotide-binding domain and leucine-rich repeat (NLR) family, pyrin domain-containing 3 (NLRP3) in femoral intertrochanteric fracture. Methods: This single-blind randomized controlled study included 231 patients with femoral intertrochanteric fracture treated in our hospital from January 2017 to December 2020. All patients were randomized into two groups, the FICB group ( Results: The values of HR and MAP were significantly lower after anesthesia induction in FICB groups compared with the control group. However, no significant difference was found for SpO Conclusion: Fascia iliac compartment block could reduce the postoperative pain, which might be associated with the decrease of the serum levels of NLRP3, CRP, IL-6, and TNF-

Indexed as

Femoral FracturesHip FracturesNerve BlockFasciaHumansInterleukin-6NLR Family, Pyrin Domain-Containing 3 ProteinPostoperative PainSingle-Blind MethodTumor Necrosis Factor-alphaUltrasonography, InterventionalInterleukin-6NLR Family, Pyrin Domain-Containing 3 ProteinTumor Necrosis Factor-alpha

Identifiers

PMID35620203
PMCPMC9129941
OpenAlexW4280570188

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.