Evidence map›Paper›PMID 35620164›Full record

ArticleChronic diseases and translational medicine2022

Metabolic profile differences in ACTH-dependent and ACTH-independent Cushing syndrome.

Zhengyang Li, Chen Zhang, Chong Geng, Yongfeng Song

Abstract read
In one paragraph

Article in Chronic diseases and translational medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Uric Acid Metabolic Disorders in Pituitary-Target Gland Axis.Diabetes, metabolic syndrome and obesity : targets and therapy · 2024
    Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Zhengyang LiDepartment of Endocrinology Shandong Provincial Hospital Affiliated to Shandong First Medical University Jinan Shandong 250021 China.
Chen ZhangDepartment of Endocrinology Shandong Provincial Hospital Affiliated to Shandong First Medical University Jinan Shandong 250021 China.
Chong GengDepartment of Breast and Thyroid Surgery Shandong Provincial Hospital Affiliated to Shandong First Medical University Jinan Shandong 250021 China.
Yongfeng SongDepartment of Endocrinology Shandong Provincial Hospital Affiliated to Shandong First Medical University Jinan Shandong 250021 China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The most common etiologies of Cushing's syndrome (CS) are adrenocorticotropic hormone (ACTH)-producing pituitary adenoma (pitCS) and primary adrenal gland disease (adrCS), both of which burden patients with metabolic disturbance. The aim of this study was to compare the metabolic features of pitCS and adrCS patients. Methods: A retrospective review including 114 patients (64 adrCS and 50 pitCS) diagnosed with CS in 2009-2019 was performed. Metabolic factors were then compared between pitCS and adrCS groups. Results: Regarding sex, females suffered both adrCs (92.2%) and pitCS (88.0%) more frequently than males. Regarding age, patients with pitCS were diagnosed at a younger age (35.40 ± 11.94 vs. 39.65 ± 11.37 years, Conclusions: Although adrCS and pitCS had different pathogenetic mechanisms, different severities of hypercortisolemia, and different diabetes prevalences, both etiologies had similar metabolic characteristics.

Indexed as

adrenal Cushing'sCushing's syndromemetabolic disturbancepituitary Cushing's

Identifiers

PMID35620164
PMCPMC9128563

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.