Evidence map›Paper›PMID 35619827›Full record

ArticleFrontiers in public health2022

A Web-Based Prognostic Model for Pediatric Genitourinary Rhabdomyosarcoma: Analysis of Population-Based Cohort With External Validation.

Jiayi Li, Yangyue Huang, Yunpeng Li, Pei Liu, Haiyan Cheng, Hongcheng Song, Ning Sun, Mina Ayad Shamil, Weiping Zhang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Jiayi LiNational Center for Children's Health, Department of Surgical Urology, Beijing Children's Hospital, Capital Medical University, Beijing, China.
Yangyue HuangNational Center for Children's Health, Department of Surgical Urology, Beijing Children's Hospital, Capital Medical University, Beijing, China.
Yunpeng LiNational Center for Children's Health, Department of Surgical Urology, Beijing Children's Hospital, Capital Medical University, Beijing, China.
Pei LiuNational Center for Children's Health, Department of Surgical Urology, Beijing Children's Hospital, Capital Medical University, Beijing, China.
Haiyan ChengNational Center for Children's Health, Department of Surgical Oncology, Beijing Children's Hospital, Capital Medical University, Beijing, China.
Hongcheng SongNational Center for Children's Health, Department of Surgical Urology, Beijing Children's Hospital, Capital Medical University, Beijing, China.
Ning SunNational Center for Children's Health, Department of Surgical Urology, Beijing Children's Hospital, Capital Medical University, Beijing, China.
Mina Ayad ShamilInternational School, Capital Medical University, Beijing, China.
Weiping ZhangNational Center for Children's Health, Department of Surgical Urology, Beijing Children's Hospital, Capital Medical University, Beijing, China.
Beijing Children’s Hospital · CNCapital Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: We conduct an analysis of data from the Surveillance, Epidemiology, and End Results (SEER) database, intending to identify prognostic factors of pediatric genitourinary rhabdomyosarcoma (PGU-RMS). Prognostic nomogram and web-based calculator were developed for potential clinical use. Methods: Data of PGU-RMS patients were extracted from the SEER database as training and internal validation cohort, patients diagnosed as PGU-RMS from 2001 to 2015 in Beijing Children's Hospital were collected as an external validation cohort. We used log-rank tests to seek risk factors on the overall survival (OS) in the overall SEER cohort, tumor site subgroups, radiation subgroups, and metastasis subgroups. The univariable and multivariate Cox regression analyses were applied to establish the prognosis model. Results: A total of 372 PGU-RMS patients in SEER and 84 patients from our center were included. 1-, 3-, and 5-year OS of the overall SEER cohort were 95.8, 82.1, and 78.8%. Subgroup analysis indicated that tumors located in the prostate/bladder were associated with a worse prognosis than the paratesticular, female genital system, and other sites ( Conclusion: A comprehensive analysis of OS for PGU-RMS patients was conducted based on population cohort. The established prognosis nomogram has been fully validated and evaluated, exhibits better performance than the IRSG pretreatment stage system. Furthermore, a web-based risk calculator was developed to optimize clinical decisions.

Indexed as

RhabdomyosarcomaChildFemaleHumansInfantInternetMaleNeoplasm StagingPrognosisProportional Hazards ModelsSEER Programgenitourinarynomogramoverall survivalprognosisRhabdomyosarcomaweb-based risk calculator

Identifiers

PMID35619827
PMCPMC9127601
OpenAlexW4229439191

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.