Evidence map›Paper›PMID 35619760›Full record

ArticleComputational intelligence and neuroscience2022

RGD-Hydrogel Improves the Therapeutic Effect of Bone Marrow-Derived Mesenchymal Stem Cells on Phosgene-Induced Acute Lung Injury in Rats.

Jianwen Ding, Yu Dun, Daikun He, Yiru Shao, Fuli Liu, Lin Zhang, Jie Shen

Open access · hybridAbstract read
In one paragraph

Article in Computational intelligence and neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Review
  6. Peptide Hydrogels and Nanostructures Controlling Biological Machinery.Langmuir : the ACS journal of surfaces and colloids · 2023
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Jianwen DingCenter of Emergency and Critical Medicine, Jinshan Hospital of Fudan University, 201508 Shanghai, China.ORCID https://orcid.org/0000-0001-7414-2229
Yu DunCenter of Emergency and Critical Medicine, Jinshan Hospital of Fudan University, 201508 Shanghai, China.ORCID https://orcid.org/0000-0003-2018-1542
Daikun HeCenter of Emergency and Critical Medicine, Jinshan Hospital of Fudan University, 201508 Shanghai, China.ORCID https://orcid.org/0000-0002-0137-5678
Yiru ShaoCenter of Emergency and Critical Medicine, Jinshan Hospital of Fudan University, 201508 Shanghai, China.ORCID https://orcid.org/0000-0003-1073-5257
Fuli LiuCenter of Emergency and Critical Medicine, Jinshan Hospital of Fudan University, 201508 Shanghai, China.ORCID https://orcid.org/0000-0001-6320-5132
Lin ZhangCenter of Emergency and Critical Medicine, Jinshan Hospital of Fudan University, 201508 Shanghai, China.ORCID https://orcid.org/0000-0002-0950-7145
Jie ShenCenter of Emergency and Critical Medicine, Jinshan Hospital of Fudan University, 201508 Shanghai, China.ORCID https://orcid.org/0000-0001-5422-5393
Fudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mesenchymal stem cells (MSCs) have promising potential in the treatment of various diseases, such as the therapeutic effect of bone marrow-derived MSCs for phosgene-induced acute lung injury (P-ALI). However, MSC-related therapeutics are limited due to poor cell survival, requiring appropriate MSC delivery systems to maximise therapeutic capacity. Biomaterial RGD-hydrogel is a potential cell delivery vehicle as it can mimic the natural extracellular matrix and provide cell adhesion support. The application of RGD-hydrogel in the MSC treatment of respiratory diseases is scarce. This study reports that RGD-hydrogel has good biocompatibility and can increase the secretion of Angiopoietin-1, hepatocyte growth factor, epidermal growth factor, vascular endothelial cell growth factor, and interleukin-10

Indexed as

Acute Lung InjuryMesenchymal Stem CellsMesenchymal Stem Cell TransplantationPhosgeneAnimalsBone MarrowHydrogelsOligopeptidesRatsHydrogelsOligopeptidesPhosgene

Identifiers

PMID35619760
PMCPMC9129938
OpenAlexW4280543809

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.