ArticleFrontiers in cellular and infection microbiology2022
A Microfluidic Chip for Studies of the Dynamics of Antibiotic Resistance Selection in Bacterial Biofilms.
Article in Frontiers in cellular and infection microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Organ-on-chip (OoC) and nano-biomaterials: next generation of precision oral and dental healthcare research.Journal of nanobiotechnology · 2026Review
- Characterizing Spatiotemporal Expansion of Pseudomonas aeruginosa Communities in Polymer and Mucin Gel Environments.Biotechnology and bioengineering · 2026Article
- A dual-loop chemostat to investigate multi-species biofilms on implant surfaces under adjustable flow conditions.Frontiers in microbiology · 2026Article
- Microfluidics to Meet Antibiotic Resistance: A Growing Research Frontier.Antibiotics (Basel, Switzerland) · 2025Review
- Cell-to-Cell and Patient-to-Patient Variability in Antimicrobial Resistance.Microorganisms · 2025Review
- A Scalable Microfluidic Platform for Bacterial Cellulose Production and Characterization.ACS omega · 2025Article
- Fabrication and Application of a Microfluidic Chip for Biofilm Cultivation and Analysis under Controlled Flow.ACS omega · 2025Article
- Droplet microfluidics-based detection of rare antibiotic-resistant subpopulations inScience advances · 2025Article
- Resolving spatiotemporal dynamics in bacterial multicellular populations: approaches and challenges.Microbiology and molecular biology reviews : MMBR · 2025Review
- In Vitro Resistance-Predicting Studies and In Vitro Resistance-Related Parameters-A Hit-to-Lead Perspective.Pharmaceuticals (Basel, Switzerland) · 2024Review
- Microfluidic Platform with Precisely Controlled Hydrodynamic Parameters and Integrated Features for Generation of Microvortices to Accurately Form and Monitor Biofilms in Flow.ACS biomaterials science & engineering · 2024Article
- Microbial life in slow and stopped lanes.Trends in microbiology · 2024Review
- PreventingACS applied materials & interfaces · 2024Article
- A Systematic Review on Organ-on-a-Chip in PDMS or Hydrogel in Dentistry: An Update of the Literature.Gels (Basel, Switzerland) · 2024Review
- Microfluidics for adaptation of microorganisms to stress: design and application.Applied microbiology and biotechnology · 2024Review
- Antibiofilm activity of marine microbial natural products: potential peptide- and polyketide-derived molecules from marine microbes toward targeting biofilm-forming pathogens.Journal of natural medicines · 2024Review
- Electromicrofluidic Device for Interference-Free Rapid Antibiotic Susceptibility Testing ofSensors (Basel, Switzerland) · 2023Article
- Structural Optimization Design of Microfluidic Chips Based on Fast Sequence Pair Algorithm.Micromachines · 2023Article
- Microfabrication approaches for oral research and clinical dentistry.Frontiers in dental medicine · 2023Review
- Biofilm antimicrobial susceptibility through an experimental evolutionary lens.NPJ biofilms and microbiomes · 2022Review
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Biofilms are arguably the most important mode of growth of bacteria, but how antibiotic resistance emerges and is selected in biofilms remains poorly understood. Several models to study evolution of antibiotic resistance have been developed, however, their usability varies depending on the nature of the biological question. Here, we developed and validated a microfluidic chip (Brimor) for studying the dynamics of enrichment of antibiotic-resistant bacteria in biofilms using real-time monitoring with confocal microscopy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.