ReviewResearch and practice in thrombosis and haemostasis2022
Sex-specific aspects of venous thromboembolism: What is new and what is next?
Review in Research and practice in thrombosis and haemostasis, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Incidence and risk factors of venous thromboembolism in patients with amyotrophic lateral sclerosis: a systematic review and meta-analysis.La Tunisie medicale · 2024Pooled it
- Plasma level of human epididymis protein 4 is associated with risk of future venous thromboembolism-the Trøndelag Health study.Journal of thrombosis and haemostasis : JTH · 2026Article
- A deep learning model to dynamically predict cancer-associated thromboembolism in large-scale healthcare systems.NPJ digital medicine · 2026Article
- Impact of Disease-Specific Treatment and Non-Selective Beta Blockers on Risk of PVT in Cirrhotic Patients With HCV or PBC.Liver international : official journal of the International Association for the Study of the Liver · 2026Article
- Sex Differences in Cancer-Associated Thrombosis.International journal of molecular sciences · 2026Review
- A cross-sectional analysis of all vena cava filter placement over 9-years in Brazil: trends and mortality rates in a population of over 200 million.Clinics (Sao Paulo, Brazil) · 2026Article
- Risk of deep vein thrombosis in patients with periodontitis: A nationwide population-based cohort study in Taiwan.Journal of dental sciences · 2026Article
- Risk Factors and Clinical Outcomes for Patients with Venous Thromboembolism in Kenya: Findings from the HEART Registry.Vascular health and risk management · 2026Article
- Impact of cardiovascular-kidney-metabolic syndrome staging on clinical outcomes and management of acute pulmonary embolism: A comprehensive analysis.International journal of cardiology. Heart & vasculature · 2025Article
- Deep vein thrombosis in Ethiopia: a systematic review and meta-analysis, 2025.Thrombosis journal · 2025Review
- Article
- Age- and Sex-Specific Risks of Major Cardiovascular Complications and All-Cause Mortality Following Elective Hip and Knee Arthroplasty in the Netherlands: A Dutch Hospital Data Registry Study.Arthroplasty today · 2025Article
- Trends in the Epidemiology of Deep Vein Thrombosis and Pulmonary Embolism in Patients Undergoing Surgery.Cureus · 2024Article
- High Rate of Thromboembolic Events in the Last Year of Life of Cancer Patients: A Registry Study.Cancers · 2024Article
- Validation of a pulmonary embolism risk assessment model in gynecological inpatients : Clinical trial: A single-center, retrospective study.Thrombosis journal · 2024Article
- Proportion of venous thromboembolism attributed to recognized prothrombotic genotypes in men and women.Research and practice in thrombosis and haemostasis · 2024Article
- High rate of recurrent venous thromboembolism in children and adolescents with unprovoked venous thromboembolism.Journal of thrombosis and haemostasis : JTH · 2023Article
- Sex-specific aspects of venous thromboembolism: What is new and what is next?Research and practice in thrombosis and haemostasis · 2022Review
- Mortality trends in the United States for adults with concurrent cerebrovascular disease and pulmonary embolism.Frontiers in neurologyArticle
- D-Dimer Variability Predicts Venous Thromboembolism in Postoperative Fracture Patients: A Single-Center Retrospective Cohort Study.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/HemostasisArticle
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Men seem to have a higher intrinsic risk of venous thromboembolism (VTE) than women, regardless of age. To date, this difference has not been explained. By integrating state-of-the-art research presented at the International Society on Thrombosis and Haemostasis Congress of 2021 with the available literature, we address potential explanations for this intriguing risk difference between men and women. We discuss the role of exogenous and endogenous sex hormones as the most important known sex-specific determinants of VTE risk. In addition, we highlight clues on the role of sex hormones and VTE risk from clinical scenarios such as pregnancy and the polycystic ovary syndrome. Furthermore, we address new potential sex-specific risk factors and unanswered research questions, which could provide more insight in the intrinsic risk difference between men and women, such as body height and differences in body fat distribution, leading to dysregulation of metabolism and inflammation.
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