Evidence map›Paper›PMID 35619598›Full record

ReviewFrontiers in behavioral neuroscience2022

Research Progress on the Role of Vitamin D in Autism Spectrum Disorder.

Jing Wang, Haoyu Huang, Chunming Liu, Yangping Zhang, Wenjuan Wang, Zhuo Zou, Lei Yang, Xuemei He, Jinting Wu, Jing Ma and 1 more

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in behavioral neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 36 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Review
  5. The Role of GCH1 Deficiency and Tetrahydrobiopterin in Mental Health.International journal of molecular sciences · 2025
    Article
  6. Article
  7. Autism Spectrum Disorder and Dietary Intake of Vitamin E.Neuropsychopharmacology reports · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Jing WangDepartment of Rehabilitation, Kunming Children's Hospital, Kunming Medical University, Yunnan, China.
Haoyu HuangDepartment of Rehabilitation, Kunming Children's Hospital, Kunming Medical University, Yunnan, China.
Chunming LiuDepartment of Rehabilitation, Kunming Children's Hospital, Kunming Medical University, Yunnan, China.
Yangping ZhangDepartment of Rehabilitation, Kunming Children's Hospital, Kunming Medical University, Yunnan, China.
Wenjuan WangDepartment of Rehabilitation, Kunming Children's Hospital, Kunming Medical University, Yunnan, China.
Zhuo ZouDepartment of Rehabilitation, Kunming Children's Hospital, Kunming Medical University, Yunnan, China.
Lei YangDepartment of Rehabilitation, Kunming Children's Hospital, Kunming Medical University, Yunnan, China.
Xuemei HeDepartment of Rehabilitation, Kunming Children's Hospital, Kunming Medical University, Yunnan, China.
Jinting WuDepartment of Rehabilitation, Kunming Children's Hospital, Kunming Medical University, Yunnan, China.
Jing MaDepartment of Otolaryngology, Head and Neck Surgery, Kunming Children's Hospital, Kunming Medical University, Yunnan, China.
Yun LiuDepartment of Rehabilitation, Kunming Children's Hospital, Kunming Medical University, Yunnan, China.
Kunming Medical University · CNKunming Children's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autism spectrum disorder (ASD) is a neurodevelopmental disorder that can lead to severe social behavioral difficulties, which mainly manifests as social communication and interaction disorders; narrow interests; and repetitive, stereotyped behaviors. In recent years, the prevalence of ASD has increased annually, and it has evolved from a rare disease to one with a high incidence among childhood developmental disorders. The pathogenesis of ASD is considered to be the interaction of genetic and environmental factors. There is increasing evidence that vitamin D deficiency in pregnancy and early childhood can lead to the occurrence of ASD. Studies have demonstrated that vitamin D intervention can significantly improve the symptoms of ASD, but the underlying mechanism is still unclear. Therefore, exploring the neuroprotective mechanism of vitamin D against ASD is a huge challenge currently being worked on by current basic and clinical researchers, a task which is of great significance for the clinical promotion and optimization of vitamin D in the treatment of ASD. To further clarify the relationship between vitamin D and ASD, this review summarizes the correlation between vitamin D level and ASD, the effects of vitamin D supplementation on ASD, the possible mechanism of vitamin D involved in ASD, and insights from ASD animal models.

Indexed as

autism spectrum disorderneurodevelopmental disorderpathogenesisresearch progressvitamin D

Identifiers

PMID35619598
PMCPMC9128593
OpenAlexW4229444457

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.