Evidence map›Paper›PMID 35619325›Full record

Trial reportCancer medicine2022

Phase 2 results of lisocabtagene maraleucel in Japanese patients with relapsed/refractory aggressive B-cell non-Hodgkin lymphoma.

Shinichi Makita, Go Yamamoto, Dai Maruyama, Yuki Asano-Mori, Daisuke Kaji, Revathi Ananthakrishnan, Ken Ogasawara, Lara Stepan, Claudia Schusterbauer, Nils Rettby and 2 more

Open access · goldAbstract readClinical Trial, Phase II
In one paragraph

Trial report in Cancer medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 3 countries.

Shinichi MakitaNational Cancer Center Hospital, Tokyo, Japan.ORCID 0000-0001-6609-8088
Go YamamotoToranomon Hospital, Tokyo, Japan.
Dai MaruyamaNational Cancer Center Hospital, Tokyo, Japan.
Yuki Asano-MoriToranomon Hospital, Tokyo, Japan.
Daisuke KajiToranomon Hospital, Tokyo, Japan.
Revathi AnanthakrishnanBristol Myers Squibb, Princeton, New Jersey, USA.
Ken OgasawaraBristol Myers Squibb, Princeton, New Jersey, USA.ORCID 0000-0002-4264-8927
Lara StepanBristol Myers Squibb, Princeton, New Jersey, USA.
Claudia SchusterbauerCelgene, a Bristol-Myers Squibb Company, Boudry, Switzerland.
Nils RettbyCelgene, a Bristol-Myers Squibb Company, Boudry, Switzerland.
Jens HasskarlCelgene, a Bristol-Myers Squibb Company, Boudry, Switzerland.
Koji IzutsuNational Cancer Center Hospital, Tokyo, Japan.ORCID 0000-0001-9129-8057
Bristol-Myers Squibb (Switzerland) · CHBristol-Myers Squibb (United States) · USTokyo National Hospital · JPToranomon Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The autologous anti-CD19 chimeric antigen receptor (CAR) T-cell product, lisocabtagene maraleucel (liso-cel), is administered at equal target doses of CD8

Indexed as

Immunotherapy, AdoptiveLymphoma, Large B-Cell, DiffuseAntigens, CD19Cytokine Release SyndromeHumansJapanReceptors, Chimeric AntigenThrombocytopeniaAntigens, CD19Receptors, Chimeric AntigenJapanese patientslarge B-cell lymphomalisocabtagene maraleucelnon-Hodgkin lymphomarelapsed/refractory

Identifiers

PMID35619325
PMCPMC9761090
OpenAlexW4281779501

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.