Evidence map›Paper›PMID 35619186›Full record

ArticleJournal of cardiothoracic surgery2022

Histologic evidence of tracheal stenosis directly resulting from SARS-CoV-2 tissue infiltration, a case series.

Tyler B Draeger, Sarah Tedesco, Shahriyour K Andaz, Vanessa R Gibson

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of cardiothoracic surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Tyler B DraegerDepartment of Surgery, Mount Sinai South Nassau, Icahn School of Medicine at Mount Sinai, Oceanside, NY, USA.ORCID http://orcid.org/0000-0003-0019-6974
Sarah TedescoAmerican University of Antigua College of Medicine, Collidge, Antigua and Barbuda.
Shahriyour K AndazDivision of Cardiothoracic Surgery, Department of Surgery, Mount Sinai South Nassau, Icahn School of Medicine at Mount Sinai, 1 Healthy Way, Oceanside, NY, 11572, USA. DrSAndaz@yahoo.com.
Vanessa R GibsonDivision of Cardiothoracic Surgery, Department of Surgery, Mount Sinai South Nassau, Icahn School of Medicine at Mount Sinai, 1 Healthy Way, Oceanside, NY, 11572, USA.
Icahn School of Medicine at Mount Sinai · USAmerican University of Antigua · AGMount Sinai Health System · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere has been an anecdotal increase in the incidence of tracheal stenosis that has coincided with the SARS-CoV-2 pandemic. CASE PRESENTATION: This is a case series in which we report clinical and pathologic findings of two patients who subsequently developed subglottic tracheal stenosis after having been hospitalized with COVID-19 pneumonia. Histopathologic analysis of tissue from these patients shows features consistent with tissue infiltrated with SARS-CoV-2 virus, namely multinucleated syncytial cells with prominent nucleoli.

conclusionOur findings directly implicate SARS-CoV-2 in the pathogenesis of tracheal stenosis.

Indexed as

COVID-19Tracheal StenosisHumansSARS-CoV-2Case seriesDilatationSARS-CoV-2Thoracic surgeryTracheal resectionTracheal stenosis

Identifiers

PMID35619186
PMCPMC9134720
OpenAlexW4281555617

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.