SynthesisWorld journal of emergency surgery : WJES2022
Meta-analysis of the clinical efficacy of laparoscopic appendectomy in the treatment of acute appendicitis.
Synthesis in World journal of emergency surgery : WJES, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 32 citations in OpenAlex.
- Evidence map of appendicitis - a living systematic review with meta-analyses.Langenbeck's archives of surgery · 2026Pooled it
- Daytime versus nighttime appendectomy in term of complications and clinical outcomes: a meta-analysis.International journal of colorectal disease · 2024Pooled it
- Laparoscopic-assisted transversus abdominis plane block versus port-site infiltration in appendicectomy: multicentre randomized clinical trial.The British journal of surgery · 2025Trial
- Appendoscope-Assisted Endoscopic Retrograde Appendicitis Therapy Versus Antibiotic Monotherapy for Acute Uncomplicated Appendicitis.Digestive diseases and sciences · 2026Article
- Laparoscopic and Robotic Appendectomy: Efficiency and Cost Comparison.Journal of surgery and research · 2026Article
- Article
- Mesoappendix position variations in laparoscopic appendicectomy; a new anatomical classification to guide surgical strategy.Updates in surgery · 2025Article
- Effect of rapid rehabilitation surgical nursing on patients' gastrointestinal function recovery and sleep quality after laparoscopic appendectomy.World journal of gastrointestinal surgery · 2025Article
- Laparoscopic appendectomy improves outcomes and reduces costs in rural Kenya.Surgical endoscopy · 2025Article
- Outcome of Laparoscopic Appendectomy: A Retrospective Study From a Local Secondary Referral Hospital.Cureus · 2024Article
- The diagnostic value of serum hepcidin in acute appendicitis.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2024Article
- Evaluating the surgical trainee ergonomic experience during minimally invasive abdominal surgery (ESTEEMA study).Scientific reports · 2024Article
- The Impact of Laparoscopic Appendectomy and Open Appendectomy on B7-H3-Mediated Intrinsic Immune Response in Children with Acute Suppurative Appendicitis.Journal of inflammation research · 2024Article
- Exploring the causality of appendectomy and ischaemic heart disease: a Mendelian randomization study and meta-analysis.Frontiers in cardiovascular medicine · 2024Article
- Cesena guidelines: WSES consensus statement on laparoscopic-first approach to general surgery emergencies and abdominal trauma.World journal of emergency surgery : WJES · 2023Article
- Training curriculum in minimally invasive emergency digestive surgery: 2022 WSES position paper.World journal of emergency surgery : WJES · 2023Review
- Laparoscopic Appendectomy Is Superior in Patients with Higher Fat Thickness.JSLS : Journal of the Society of Laparoendoscopic SurgeonsArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis paper compares the postoperative recovery of patients with acute appendicitis (AA) after laparoscopic appendectomy (LA) and open appendectomy (OA), aiming to determine the optimal diagnosis and treatment plan for appendectomy.
methodsRelated literature was retrieved from PubMed, Web of Science, Embase, CNKI and Wanfang databases. Articles on LA and OA for AA published between 2010 and 2021 were selected to extract data. Besides, Stata16.0 was used for meta-analysis.
resultsA total of 777 articles were retrieved, and 16 of them were finally selected. Totally, 1251 patients underwent LA, while 898 patients received OA. According to the results of meta-analysis, LA was associated with lower incidence of adverse reactions [OR = 0.257, 95% CI (0.162, 0.408), P < 0.001], shorter operation time (SMD = - 1.802, 95% CI - 2.435, - 1.169; P < 0.001) and hospitalization (SMD = - 1.184, 95% CI - 1.512, - 0.856; P < 0.001). In addition, compared with the OA group, LA was found with less intraoperative blood loss (SMD = - 3.650, 95% CI - 5.088, - 2.212; P < 0.001) and shorter recovery time of gastrointestinal function (SMD = - 3.010, 95% CI - 3.816, - 2.203; P < 0.001). Aside from all these, the counts of leukocyte (SMD = - 0.432, 95% CI: - 0.775, - 0.089; P = 0.013), neutrophil (SMD = - 1.346, 95% CI - 2.560, - 0.133; P = 0.030), and C-reactive protein (SMD = - 2.391, 95% CI - 3.901, - 0.882; P = 0.002) all decreased in a significant manner after LA.
conclusionCompared with OA, LA boasts the advantages of less adverse reactions, shorter operation time and hospitalization, fewer complications, and lower inflammatory response, evidencing its safety and feasibility of applying in the treatment of AA.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.