Evidence map›Paper›PMID 35618970›Full record

ArticleBulletin of experimental biology and medicine2022

Cytokine Production in Whole Blood Cells Culture of Patients with Alcohol Dependence and Autologous Plasma Oxidative Stress Markers.

T P Vetlugina, V D Prokopieva, E V Epimakhova, A S Boiko, V B Nikitina, N A Bokhan

Abstract read
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In one paragraph

Article in Bulletin of experimental biology and medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

T P VetluginaResearch Institute of Mental Health, Tomsk National Research Medical Center, Russian Academy of Sciences, Tomsk, Russia. vetluga21@mail.ru.
V D ProkopievaResearch Institute of Mental Health, Tomsk National Research Medical Center, Russian Academy of Sciences, Tomsk, Russia.
E V EpimakhovaResearch Institute of Mental Health, Tomsk National Research Medical Center, Russian Academy of Sciences, Tomsk, Russia.
A S BoikoResearch Institute of Mental Health, Tomsk National Research Medical Center, Russian Academy of Sciences, Tomsk, Russia.
V B NikitinaResearch Institute of Mental Health, Tomsk National Research Medical Center, Russian Academy of Sciences, Tomsk, Russia.
N A BokhanResearch Institute of Mental Health, Tomsk National Research Medical Center, Russian Academy of Sciences, Tomsk, Russia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We studied spontaneous production of a spectrum of proinflammatory cytokines by cultured whole blood cells from men with alcohol dependence at the stage of withdrawal syndrome and oxidative stress markers (carbonylated proteins and TBA-reactive substances) in the plasma of these blood samples. Enhanced production of cytokines by blood cells and increased concentrations of oxidative stress markers in the autologous plasma were revealed in comparison with the corresponding parameters in the control (blood from healthy men). Direct correlations were found between the levels of spontaneous cytokine production by blood cells from subjects with alcohol dependence and the concentration of oxidized proteins and lipids in autologous plasma.

Indexed as

AlcoholismBiomarkersBlood CellsCytokinesHumansMaleOxidative StressBiomarkersCytokinesalcohol dependencemarkers of oxidative stressspontaneous cytokine production

Identifiers

PMID35618970

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.