Evidence map›Paper›PMID 35618898›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2022

Acellular Myocardial Scaffolds and Slices Fabrication, and Method for Applying Mechanical and Electrical Simulation to Tissue Construct.

Bo Wang, Mickey Shah, Lakiesha N Williams, Amy L de Jongh Curry, Yi Hong, Ge Zhang, Jun Liao

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Bo WangJoint Department of Biomedical Engineering, Marquette University and the Medical College of Wisconsin, Milwaukee, WI, USA.
Mickey ShahDepartment of Biomedical Engineering, The University of Akron, Akron, OH, USA.
Lakiesha N WilliamsDepartment of Biomedical Engineering, University of Florida, Gainesville, FL, USA.
Amy L de Jongh CurryDepartment of Biomedical Engineering, University of Memphis, Memphis, TN, USA.
Yi HongDepartment of Bioengineering, University of Texas at Arlington, Arlington, TX, USA.
Ge ZhangDepartment of Biomedical Engineering, The University of Akron, Akron, OH, USA. ge10@uakron.edu.
Jun LiaoDepartment of Bioengineering, University of Texas at Arlington, Arlington, TX, USA. jun.liao@uta.edu.

Funding

CONTROL OF CARDIAC FIBROSIS TO PREVENT CARDIAC FUNCTION DETERIORATIONR01EB022018 · NIBIB · WASHINGTON UNIVERSITY · PI GUAN, JIANJUN · 2016 to 2018
$1.1M
Bioactive injectable blends for cardiac stem cell recruitmentR15HL140503 · NHLBI · UNIVERSITY OF TEXAS ARLINGTON · PI HONG, YI · 2018 to 2018
$460k
Reinforce Cell Sheets with Acellular Porcine Myocardial Scaffolds: Application in Cardiac RepairR15HL122949 · NHLBI · UNIVERSITY OF AKRON · PI ZHANG, GE · 2015 to 2015
$460k
Treatment of cardiac reperfusion injury by optimizing the mitochondrial membraneR15HL122922 · NHLBI · EAST CAROLINA UNIVERSITY · PI SHAIKH, SAAME R · 2015 to 2015
$434k
A Controlled Septal Ablation for Inoperable Hypertrophic CardiomyopathyR15HL159599 · NHLBI · UNIVERSITY OF TEXAS ARLINGTON · PI LIAO, JUN · 2022 to 2022
$433k
Tissue Engineered Cardiac Patches: Multifaceted Stimulation of Stem Cells in DeceR15HL097321 · NHLBI · MISSISSIPPI STATE UNIVERSITY · PI LIAO, JUN · 2009 to 2009
$205k
NHLBI NIH HHS R15 HL097321NHLBI NIH HHS R15 HL122922NHLBI NIH HHS R15 HL122949NHLBI NIH HHS R15 HL140503NHLBI NIH HHS R15 HL159599NIBIB NIH HHS R01 EB022018
6 · The paper itself

Abstract

Cardiac tissue engineering/regeneration using decellularized myocardium has attracted great research attention due to its potential benefit to myocardial infarction (MI) treatment. Here, we described an optimal decellularization protocol to generate 3D porcine myocardial scaffolds with well-preserved cardiomyocyte lacunae, myocardial slices as a biomimetic cell culture and delivery platform, and a multi-stimulation bioreactor that is able to provide coordinated mechanical and electrical stimulations for facilitating cardiac construct development.

Indexed as

Tissue EngineeringTissue ScaffoldsAnimalsCell Culture TechniquesMyocardiumMyocytes, CardiacSwineAcellular myocardial scaffoldsAcellular myocardial slicesBioreactorCardiac tissue engineering/regenerationDecellularizationElectrical simulationMechanical simulation

Identifiers

PMID35618898
PMCPMC9811994

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.