Evidence map›Paper›PMID 35618780›Full record

ReviewAnnals of hematology2022

Oncology stewardship in acute myeloid leukemia.

Madeleine A Ochs, Bernard L Marini, Anthony J Perissinotti, Charles E Foucar, Kristen Pettit, Patrick Burke, Dale L Bixby, Lydia L Benitez

Abstract readReview
PubMed Publisher
In one paragraph

Review in Annals of hematology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Oncology stewardship: Role of the pharmacists for contribution in low and middle-income countries.Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Madeleine A OchsDepartment of Pharmacy Services and Clinical Pharmacy, Michigan Medicine, 1540 E. Hospital Dr, Ann Arbor, MI, 48109, USA.
Bernard L MariniDepartment of Pharmacy Services and Clinical Pharmacy, Michigan Medicine, 1540 E. Hospital Dr, Ann Arbor, MI, 48109, USA.
Anthony J PerissinottiDepartment of Pharmacy Services and Clinical Pharmacy, Michigan Medicine, 1540 E. Hospital Dr, Ann Arbor, MI, 48109, USA.
Charles E FoucarDepartment of Internal Medicine and Division of Hematology and Oncology, Michigan Medicine, Ann Arbor, MI, USA.
Kristen PettitDepartment of Internal Medicine and Division of Hematology and Oncology, Michigan Medicine, Ann Arbor, MI, USA.
Patrick BurkeDepartment of Internal Medicine and Division of Hematology and Oncology, Michigan Medicine, Ann Arbor, MI, USA.
Dale L BixbyDepartment of Internal Medicine and Division of Hematology and Oncology, Michigan Medicine, Ann Arbor, MI, USA.
Lydia L BenitezDepartment of Pharmacy Services and Clinical Pharmacy, Michigan Medicine, 1540 E. Hospital Dr, Ann Arbor, MI, 48109, USA. lbenitez@med.umich.edu.
Michigan Medicine · USUniversity of Michigan–Ann Arbor · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, an explosion of novel agents has shifted the treatment paradigm for patients with acute myeloid leukemia. The optimal place in therapy for many of these novel agents remains unknown due to limited guidance from national guidelines and the way these agents were studied prior to entering the market. A critical evaluation of the literature and incorporation of oncology stewardship principles can be helpful in determining an optimal place for these agents while being mindful of the overall cost that is associated with therapies. The purpose of this review is to critically evaluate the efficacy and safety data for five controversial agents and provide examples of the use of stewardship practices in determining their place in the treatment of acute myeloid leukemia.

Indexed as

Leukemia, Myeloid, AcuteMedical OncologyHumansAcute myeloid leukemiaFinancial toxicityNovel agentsOncology stewardship

Identifiers

PMID35618780
OpenAlexW4281563032

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.