Evidence map›Paper›PMID 35618476›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2022

Nuclear Medicine and Artificial Intelligence: Best Practices for Evaluation (the RELAINCE Guidelines).

Abhinav K Jha, Tyler J Bradshaw, Irène Buvat, Mathieu Hatt, Prabhat Kc, Chi Liu, Nancy F Obuchowski, Babak Saboury, Piotr J Slomka, John J Sunderland and 5 more

Abstract read
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Guideline
  4. Article
  5. Revisiting Perfusion in the Forgotten Right Ventricle: Artificial Intelligence-Enhanced Quantification on PET/CT.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2026
    Article
  6. Applications of artificial intelligence in nuclear medicine.Zeitschrift fur medizinische Physik · 2026
    Review
  7. Review
  8. Article
  9. Article
  10. Artificial intelligence for TNM staging in NSCLC: a critical appraisal of segmentation utility in [European journal of nuclear medicine and molecular imaging · 2026
    Article
  11. Comparison of multi-organ CT image segmentation tools for whole-body [European journal of nuclear medicine and molecular imaging · 2026
    Article
  12. AutoPET Challenge on Fully Automated Lesion Segmentation in Oncologic PET/CT Imaging, Part 2: Domain Generalization.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2026
    Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Artificial Intelligence-Powered Quantification of Flortaucipir PET for Detecting Tau Pathology.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025
    Article
  18. Article
  19. Summary Report of the SNMMI AI Task Force Radiomics Challenge 2024.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025
    Article
  20. Review

3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Abhinav K JhaDepartment of Biomedical Engineering and Mallinckrodt Institute of Radiology, Washington University in St. Louis, Missouri; a.jha@wustl.edu.
Tyler J BradshawDepartment of Radiology, University of Wisconsin-Madison, Madison, Wisconsin.
Irène BuvatLITO, Institut Curie, Université PSL, U1288 Inserm, Orsay, France.
Mathieu HattLaTiM, INSERM, UMR 1101, Univ Brest, Brest, France.
Prabhat KcCenter for Devices and Radiological Health, Food and Drug Administration, Silver Spring, Maryland.
Chi LiuDepartment of Radiology and Biomedical Imaging, Yale University, Connecticut.
Nancy F ObuchowskiQuantitative Health Sciences, Cleveland Clinic, Cleveland, Ohio.
Babak SabouryDepartment of Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Maryland.
Piotr J SlomkaDepartment of Imaging, Medicine, and Cardiology, Cedars-Sinai Medical Center, California.
John J SunderlandDepartments of Radiology and Physics, University of Iowa, Iowa.
Richard L WahlMallinckrodt Institute of Radiology, Washington University in St. Louis, Missouri.
Zitong YuDepartment of Biomedical Engineering, Washington University in St. Louis, St. Louis, Missouri.
Sven ZuehlsdorffSiemens Medical Solutions USA, Inc., Hoffman Estates, Illinois.
Arman RahmimDepartments of Radiology and Physics, University of British Columbia, Canada; and.
Ronald BoellaardDepartment of Radiology & Nuclear Medicine, Cancer Centre Amsterdam, Amsterdam University Medical Centers, Netherlands.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
NCATS NIH HHS UL1 TR001863
6 · The paper itself

Abstract

An important need exists for strategies to perform rigorous objective clinical-task-based evaluation of artificial intelligence (AI) algorithms for nuclear medicine. To address this need, we propose a 4-class framework to evaluate AI algorithms for promise, technical task-specific efficacy, clinical decision making, and postdeployment efficacy. We provide best practices to evaluate AI algorithms for each of these classes. Each class of evaluation yields a claim that provides a descriptive performance of the AI algorithm. Key best practices are tabulated as the RELAINCE (Recommendations for EvaLuation of AI for NuClear medicinE) guidelines. The report was prepared by the Society of Nuclear Medicine and Molecular Imaging AI Task Force Evaluation team, which consisted of nuclear-medicine physicians, physicists, computational imaging scientists, and representatives from industry and regulatory agencies.

Indexed as

Artificial IntelligenceNuclear MedicineAlgorithmsRadionuclide Imagingartificial intelligencebest practicesclinical decision makingclinical taskevaluationgeneralizabilityPETpostdeploymentSPECTtechnical efficacy

Identifiers

PMID35618476
PMCPMC9454473

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.