ArticleAJNR. American journal of neuroradiology2022
Diagnostic Accuracy of High-Resolution 3D T2-SPACE in Detecting Cerebral Venous Sinus Thrombosis.
Article in AJNR. American journal of neuroradiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.
- Diagnostic value of MR black-blood thrombus imaging, contrast-enhanced MRI, and noncontrast-enhanced MR venography in cerebral vein thrombosis: a systematic review and meta-analysis.European radiology · 2026Pooled it
- Intracranial venous thrombosis imaging by anatomical location: an educational review with mimics and diagnostic pitfalls.Insights into imaging · 2026Article
- The evolving role of MR black-blood thrombus imaging in the diagnosis of cerebral venous thrombosis.European radiology · 2026Article
- Dural sinus thrombus volume as an independent risk factor for cortical venous involvement in patients with cerebral venous sinus thrombosis.Neuroradiology · 2026Article
- Cerebral venous sinus thrombosis secondary to nasopharyngeal abscess with Klebsiella pneumoniae infection in an elderly patient with multiple comorbidities: a case report and literature review.BMC infectious diseases · 2026Review
- Cerebral Sinovenous Thrombosis in Children With Acute Bacterial Intracranial Infection.Neurology · 2025Observational
- Differential Assessment of Internal Jugular Vein Stenosis in Patients Undergoing CT and MRI with Contrast.Tomography (Ann Arbor, Mich.) · 2024Article
- Post-Traumatic Cerebral Infarction: A Narrative Review of Pathophysiology, Diagnosis, and Treatment.Neurology international · 2024Review
- Article
- Detection of cerebral cortical vein thrombosis with high-resolution susceptibility weighted imaging - A comparison with MR venography and standard MR sequences.Neuroradiology · 2023Article
- Comparison of susceptibility-weighted angiography (SWAN) and T2 gradient-echo sequences for the detection of acute cerebral venous thrombosis.The neuroradiology journal · 2023Article
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Authors and funding
10 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeAssessment of cerebral venous sinus thrombosis on MR imaging can be challenging. The aim of this study was to evaluate the diagnostic accuracy of high-resolution 3D T2 sampling perfection with application-optimized contrasts by using different flip angle evolution (SPACE) in patients with cerebral venous sinus thrombosis and to compare its performance with contrast-enhanced 3D T1-MPRAGE. MATERIALS AND
methodsWe performed a blinded retrospective analysis of T2-SPACE and contrast-enhanced MPRAGE sequences from patients with cerebral venous sinus thrombosis and a control group. The results were compared with a reference standard, which was based on all available sequences and clinical history. Subanalyses were performed according to the venous segment involved and the clinical stage of the thrombus.
resultsSixty-three MR imaging examinations from 35 patients with cerebral venous sinus thrombosis and 51 examinations from 40 control subjects were included. The accuracy, sensitivity, and specificity calculated from the initial MR imaging examination for each patient were 100% each for T2-SPACE and 95%, 91%, and 98%, respectively, for contrast-enhanced MPRAGE. The interrater reliability was high for both sequences. In the subanalysis, the accuracy for each venous segment involved and if subdivided according to the clinical stage of thrombus was ≥95% and ≥85% for T2-SPACE and contrast-enhanced MPRAGE, respectively.
conclusionsBoth T2-SPACE and contrast-enhanced MPRAGE offer high accuracy for the detection and exclusion of cerebral venous sinus thrombosis; however, T2-SPACE showed a better overall performance and thus could be a useful tool if included in a multiparametric MR imaging protocol for the diagnosis of cerebral venous sinus thrombosis, especially in scenarios where gadolinium administration is contraindicated.
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