Evidence map›Paper›PMID 35618312›Full record

ArticleGenes & development2022

ssDNA is an allosteric regulator of the

Kevin Gozzi, Raul Salinas, Viet D Nguyen, Michael T Laub, Maria A Schumacher

Open access · diamondAbstract read
In one paragraph

Article in Genes & development, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Defence systems encoded by core genomic islands of seventh pandemicPhilosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Proteomic survey of the DNA damage response inJournal of bacteriology · 2023
    Article
  15. Proteomic survey of the DNA damage response inbioRxiv : the preprint server for biology · 2023
    Article
  16. Review
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Kevin GozziDepartment of Biology, Massachusetts Institute of Technology. Cambridge, Massachusetts 02139, USA.
Raul SalinasDepartment of Biochemistry, Duke University Medical Center, Durham, North Carolina 27710, USA.
Viet D NguyenDepartment of Biochemistry, Duke University Medical Center, Durham, North Carolina 27710, USA.
Michael T LaubDepartment of Biology, Massachusetts Institute of Technology. Cambridge, Massachusetts 02139, USA.
Maria A SchumacherDepartment of Biochemistry, Duke University Medical Center, Durham, North Carolina 27710, USA.ORCID 0000-0002-5264-1120
Duke Medical Center · USHoward Hughes Medical Institute · USMassachusetts Institute of Technology · US

Funding

User Training and OutreachP30GM124169 · NIGMS · UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB · PI PAUL David ADAMS, Gregory L Hura · 2017 to 2026
$28.6M
Deciphering fundamental biological processes involving protein-nucleic acid interactions at the molecular levelR35GM130290 · NIGMS · DUKE UNIVERSITY · PI Maria Schumacher · 2019 to 2026
$4.9M
Cell Cycle Regulation in Caulobacter CrescentusR01GM082899 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI LAUB, MICHAEL · 2008 to 2020
$3.8M
Pilatus 6mS10OD021832 · OD · UNIVERSITY OF CALIFORNIA BERKELEY · PI ADAMS, PAUL DAVID · 2016 to 2016
$980k
Howard Hughes Medical InstituteNIGMS NIH HHS P30 GM124169NIGMS NIH HHS R01 GM082899NIGMS NIH HHS R35 GM130290NIH HHS S10 OD021832
6 · The paper itself

Abstract

DNA damage repair systems are critical for genomic integrity. However, they must be coordinated with DNA replication and cell division to ensure accurate genomic transmission. In most bacteria, this coordination is mediated by the SOS response through LexA, which triggers a halt in cell division until repair is completed. Recently, an SOS-independent damage response system was revealed in

Indexed as

Bacterial ProteinsCaulobacter crescentusDNA DamageDNA, Single-StrandedTranscription FactorsBacterial ProteinsDNA, Single-StrandedTranscription FactorsCaulobacter crescentusDNA repairDriDssDNAtranscriptional activatorWYL motif

Identifiers

PMID35618312
PMCPMC9186387
OpenAlexW4281571790

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.