Evidence map›Paper›PMID 35618268›Full record

ArticleImmunoHorizons2022

Variability in Severe Acute Respiratory Syndrome Coronavirus 2 IgG Antibody Affinity to Omicron and Delta Variants in Convalescent and Community mRNA-Vaccinated Individuals.

Michael K Tu, Samantha H Chiang, David T W Wong, Charles M Strom

Open access · goldAbstract read
In one paragraph

Article in ImmunoHorizons, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 58% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Saliva diagnostics: Salivaomics, saliva exosomics, and saliva liquid biopsy.Journal of the American Dental Association (1939) · 2023
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Michael K TuLiquid Diagnostics LLC, San Clemente, CA; and.ORCID 0000-0002-7227-4030
Samantha H ChiangUCLA School of Dentistry, Los Angeles, CA.
David T W WongUCLA School of Dentistry, Los Angeles, CA.
Charles M StromLiquid Diagnostics LLC, San Clemente, CA; and strom@liquid-dx.com.ORCID 0000-0001-9709-0724

Funding

UC BRAID Center for Accelerated Innovation COVID-19 diagnostic project developmentU54HL119893 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI PALAZZOLO, MICHAEL J · 2013 to 2020
$18.3M
AFS/SERS Saliva-based SARS-CoV-2 Earliest Infection and Antibodies DetectionU18TR003778 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI HUANG, TONY JUN, KIM, YONG · 2021 to 2022
$1.8M
NCATS NIH HHS U18 TR003778NHLBI NIH HHS U54 HL119893
6 · The paper itself

Abstract

The emergence of the omicron and delta variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has begun a number of discussions regarding breakthrough infection, waning immunity, need and timing for vaccine boosters, and whether existing mRNA vaccines for the original SARS-CoV-2 strain are adequate. Our work leverages a biosensor-based technique to evaluate the binding efficacy of SARS-CoV-2 S1-specific salivary Abs to the omicron and delta variants using a cohort of mRNA-vaccinated (

Indexed as

COVID-19Viral VaccinesAntibodies, ViralAntibody AffinityHumansImmunoglobulin GRNA, MessengerSARS-CoV-2Antibodies, ViralImmunoglobulin GRNA, MessengerViral Vaccines

Identifiers

PMID35618268
PMCPMC10858985
OpenAlexW4282918233

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.