Evidence map›Paper›PMID 35618181›Full record

ArticleFree radical biology & medicine2022

Fluorinated diselenide nanoparticles for radiosensitizing therapy of cancer.

Miroslav Vetrik, Jan Kucka, Libor Kobera, Rafal Konefal, Volodymyr Lobaz, Ewa Pavlova, Martin Bajecny, Tomas Heizer, Jiri Brus, Ludek Sefc and 2 more

Open access · greenAbstract read
In one paragraph

Article in Free radical biology & medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Miroslav VetrikInstitute of Macromolecular Chemistry of the Czech Academy of Sciences, Heyrovsky Sq.2, 162 06, Prague 6, Czech Republic; Stanford University, Stanford School of Medicine, Stanford, CA, 94305, USA. Electronic address: miroslav.vetrik@gmail.com.
Jan KuckaInstitute of Macromolecular Chemistry of the Czech Academy of Sciences, Heyrovsky Sq.2, 162 06, Prague 6, Czech Republic.
Libor KoberaInstitute of Macromolecular Chemistry of the Czech Academy of Sciences, Heyrovsky Sq.2, 162 06, Prague 6, Czech Republic.
Rafal KonefalInstitute of Macromolecular Chemistry of the Czech Academy of Sciences, Heyrovsky Sq.2, 162 06, Prague 6, Czech Republic.
Volodymyr LobazInstitute of Macromolecular Chemistry of the Czech Academy of Sciences, Heyrovsky Sq.2, 162 06, Prague 6, Czech Republic.
Ewa PavlovaInstitute of Macromolecular Chemistry of the Czech Academy of Sciences, Heyrovsky Sq.2, 162 06, Prague 6, Czech Republic.
Martin BajecnyCenter for Advanced Preclinical Imaging (CAPI), First Faculty of Medicine, Charles University, Salmovska 3, Prague 2, 120 00, Czech Republic.
Tomas HeizerCenter for Advanced Preclinical Imaging (CAPI), First Faculty of Medicine, Charles University, Salmovska 3, Prague 2, 120 00, Czech Republic.
Jiri BrusInstitute of Macromolecular Chemistry of the Czech Academy of Sciences, Heyrovsky Sq.2, 162 06, Prague 6, Czech Republic.
Ludek SefcCenter for Advanced Preclinical Imaging (CAPI), First Faculty of Medicine, Charles University, Salmovska 3, Prague 2, 120 00, Czech Republic.
Guillem PratxStanford University, Stanford School of Medicine, Stanford, CA, 94305, USA.
Martin HrubyInstitute of Macromolecular Chemistry of the Czech Academy of Sciences, Heyrovsky Sq.2, 162 06, Prague 6, Czech Republic.
Czech Academy of Sciences, Institute of Macromolecular Chemistry · CZCharles University · CZStanford University · US

Funding

Translational Oncology Research Program (Project-005)P30CA124435 · NCI · STANFORD UNIVERSITY · PI Vittorio Sebastiano · 2007 to 2026
$71.4M
NCI NIH HHS P30 CA124435
6 · The paper itself

Abstract

Radiation resistance of cancer cells represents one of the major challenges in cancer treatment. The novel self-assembled fluoralkylated diselenide nanoparticles (fluorosomes) based on seleno-l-cystine (17FSe

Indexed as

Antineoplastic AgentsNanoparticlesNeoplasmsRadiation-Sensitizing AgentsAnimalsGlutathioneHydrogen PeroxideMiceOxidation-ReductionAntineoplastic AgentsGlutathioneHydrogen PeroxideRadiation-Sensitizing AgentsDiselenideFluorosomesHypoxiaRadiosensitizersRedox systemsSelf-assembly nanoparticles

Identifiers

PMID35618181
PMCPMC12747492
OpenAlexW4281386572

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.