Evidence map›Paper›PMID 35618084›Full record

Trial reportBrazilian journal of anesthesiology (Elsevier)

Efficacy of dexmedetomidine versus magnesium sulfate as an adjuvant to intraperitoneal bupivacaine in pediatric laparoscopic surgery: a randomized clinical trial.

Seham Mohamed Moeen, Ola Mahmoud Wahba, Ahmed Mohamed Mandour, Noha Abdel Ghany, Mohamed AbdelKader Osman, Tarek Abdelazeem Sabra, Mohammed Hamada Takrouney, Ahmed Mohamed Moeen

Open access · diamondAbstract readRandomized Controlled TrialComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Brazilian journal of anesthesiology (Elsevier). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Seham Mohamed MoeenAssiut University, Faculty of Medicine, Department of Anesthesia, Intensive Care, and Pain Management, Assiut, Egypt. Electronic address: seham.moeen@aun.edu.eg.
Ola Mahmoud WahbaAssiut University, Faculty of Medicine, Department of Anesthesia, Intensive Care, and Pain Management, Assiut, Egypt.
Ahmed Mohamed MandourAssiut University, Faculty of Medicine, Department of Anesthesia, Intensive Care, and Pain Management, Assiut, Egypt.
Noha Abdel GhanyAssiut University, Faculty of Medicine, Department of Anesthesia, Intensive Care, and Pain Management, Assiut, Egypt.
Mohamed AbdelKader OsmanAssiut University, Faculty of Medicine, General Surgery Pediatric Division, Assiut, Egypt.
Tarek Abdelazeem SabraAssiut University, Faculty of Medicine, General Surgery Pediatric Division, Assiut, Egypt.
Mohammed Hamada TakrouneyAssiut University, Faculty of Medicine, General Surgery Pediatric Division, Assiut, Egypt.
Ahmed Mohamed MoeenAssiut University, Faculty of Medicine, Assiut Urology and Nephrology Hospital, Assiut, Egypt.
Assiut University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe evaluated the efficacy of dexmedetomidine versus magnesium sulfate as an adjuvant to intraperitoneal (IP) bupivacaine in pediatric laparoscopic inguinal herniorrhaphy.

methodsNinety-seven male children, ASA I-II, 1-6 years old, undergoing laparoscopic inguinal herniorrhaphy, were randomized to receive before peritoneal insufflation, IP 2 mg.kg

resultsFLACC scores were significantly higher in Group C than in the other two groups at 6, 8, 12, 18, 24, and 48 hours after surgery with no differences between Groups D and M. Rescue analgesia was significantly higher in Group C with none of the children in Groups D and M requiring rescue analgesia (p = 0.001). Times to first flatus and stool, emetic events, and adverse effects did not differ among groups. Times to return to normal functional activity were comparable in all groups. Parents' satisfaction was greater in Groups D and M than in Group C (p = 0.026).

conclusionDexmedetomidine and magnesium sulfate added to IP bupivacaine improved the analgesia afforded by bupivacaine in the first two postoperative days in children scheduled for laparoscopic herniorrhaphy.

Indexed as

Anesthetics, LocalBupivacaineDexmedetomidineLaparoscopyMagnesium SulfatePostoperative PainAdjuvants, AnesthesiaChildChild, PreschoolDouble-Blind MethodHernia, InguinalHerniorrhaphyHumansInfantInjections, IntraperitonealMaleAdjuvants, AnesthesiaAnesthetics, LocalBupivacaineDexmedetomidineMagnesium SulfateDexmedetomidineIntraperitoneal analgesiaLaparoscopic surgeryMagnesium sulfatePediatric

Identifiers

PMID35618084
PMCPMC11440777
OpenAlexW4281381927

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.