Evidence map›Paper›PMID 35618046›Full record

ReviewThe Journal of allergy and clinical immunology2022

Current vaccine strategies against SARS-CoV-2: Promises and challenges.

Drishya Kurup, Jacob Myers, Matthias J Schnell

Abstract readReview
In one paragraph

Review in The Journal of allergy and clinical immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. COVID-19 and Pregnancy: Key Findings.Scandinavian journal of immunology · 2026
    Review
  2. Article
  3. Article
  4. COVID-19 vaccine uptake among young adults: Influence of asthma and sociodemographic factors.The journal of allergy and clinical immunology. Global · 2024
    Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Drishya KurupDepartment of Microbiology and Immunology, Sidney Kimmel Medical College, Philadelphia, Pa.
Jacob MyersDepartment of Microbiology and Immunology, Sidney Kimmel Medical College, Philadelphia, Pa.
Matthias J SchnellDepartment of Microbiology and Immunology, Sidney Kimmel Medical College, Philadelphia, Pa; Jefferson Vaccine Center, Thomas Jefferson University, Philadelphia, Pa. Electronic address: Matthias.Schnell@jefferson.edu.

Funding

Toward a protective Covid-19 vaccine utilizing an established vector platformR21AI158044 · NIAID · THOMAS JEFFERSON UNIVERSITY · PI SCHNELL, MATTHIAS JOHANNES · 2020 to 2020
$429k
NIAID NIH HHS R21 AI158044
6 · The paper itself

Abstract

In the years since the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic began and spread across the globe, lessons have been learned about the challenges and opportunities that a pandemic brings to humankind. Researchers have produced many vaccines at unprecedented speed to protect people, but they have also been cognizant of the challenges presented by a new and unexpected infectious disease. The scope of this review is to examine the path of vaccine discovery so far and identify potential targets. Here, we provide insight into the leading vaccines and their advantages and challenges. We discuss the emerging mutations within the SARS-CoV-2 spike protein and other issues that need to be addressed to overcome coronavirus disease 2019 (COVID-19) completely. Future research is needed to develop a cheap, temperature-stable vaccine providing long-term immunity that protects the upper respiratory tract.

Indexed as

COVID-19COVID-19 VaccinesAntibodies, ViralHumansSARS-CoV-2Spike Glycoprotein, CoronavirusAntibodies, ViralCOVID-19 VaccinesSpike Glycoprotein, Coronavirusspike protein, SARS-CoV-2Approved vaccinesCOVID-19preclinical vaccinesSARS-CoV-2side effectsvaccine hesitancyvaccine strategiesvariants of concern

Identifiers

PMID35618046
PMCPMC9126615

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.