Evidence map›Paper›PMID 35617913›Full record

ArticleCarbohydrate research2022

Binding of synthetic carbohydrate receptors to enveloped virus glycans: Insights from molecular dynamics simulations.

Beicer Tapia, Genrietta Yagudayeva, M Fernando Bravo, Khushabu Thakur, Adam B Braunschweig, Mateusz Marianski

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Carbohydrate research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Monosaccharide Binding to Synthetic Carbohydrate Receptor Microarrays.The journal of physical chemistry. C, Nanomaterials and interfaces · 2025
    Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Beicer TapiaDepartment of Chemistry and Biochemistry, Hunter College, The City University of New York, 695 Park Ave, New York, NY, 10065, USA; The PhD Program in Biochemistry, The Graduate Center of The City University of New York, 365 5th Ave, New York, NY, 10016, USA.
Genrietta YagudayevaDepartment of Chemistry and Biochemistry, Hunter College, The City University of New York, 695 Park Ave, New York, NY, 10065, USA.
M Fernando BravoDepartment of Chemistry and Biochemistry, Hunter College, The City University of New York, 695 Park Ave, New York, NY, 10065, USA.
Khushabu ThakurAdvanced Science Research Center of The City University of New York, 85 Nicolas Terrace, New York, NY, 10031, USA.
Adam B BraunschweigDepartment of Chemistry and Biochemistry, Hunter College, The City University of New York, 695 Park Ave, New York, NY, 10065, USA; The PhD Program in Biochemistry, The Graduate Center of The City University of New York, 365 5th Ave, New York, NY, 10016, USA; The PhD Program in Chemistry, The Graduate Center of The City University of New York, 365 5th Ave, New York, NY, 10016, USA; Advanced Science Research Center of The City University of New York, 85 Nicolas Terrace, New York, NY, 10031, USA.
Mateusz MarianskiDepartment of Chemistry and Biochemistry, Hunter College, The City University of New York, 695 Park Ave, New York, NY, 10065, USA; The PhD Program in Biochemistry, The Graduate Center of The City University of New York, 365 5th Ave, New York, NY, 10016, USA; The PhD Program in Chemistry, The Graduate Center of The City University of New York, 365 5th Ave, New York, NY, 10016, USA; Advanced Science Research Center of The City University of New York, 85 Nicolas Terrace, New York, NY, 10031, USA. Electronic address: mmarians@hunter.cuny.edu.
The Graduate Center, CUNY · USCity University of New York · US

Funding

Hopping Sugars: molecular mechanism of protonatedglycans rearrangementSC2GM135145 · NIGMS · HUNTER COLLEGE · PI MARIANSKI, MATEUSZ RYSZARD · 2020 to 2022
$468k
NIGMS NIH HHS SC2 GM135145
6 · The paper itself

Abstract

Can envelope glycans be targeted to stop viral pandemics? Here we address this question by using molecular dynamics simulations to study the binding between 10 synthetic carbohydrate receptors (SCRs) and the 33 N-glycans most commonly found on the surfaces of enveloped viruses, including Zika virus and SARS-CoV-2. Based on association quotients derived from these simulations, we classified the SCRs as weak binders, promiscuous binders, or selective binders. The SCRs almost exclusively associate at the Man

Indexed as

COVID-19Receptors, ArtificialZika VirusZika Virus InfectionCarbohydratesHumansMolecular Dynamics SimulationPolysaccharidesSARS-CoV-2CarbohydratesPolysaccharidesReceptors, ArtificialAntiviral agentsGlycansMolecular dynamics simulationsSupramolecular chemistryViruses

Identifiers

PMID35617913
PMCPMC9080030
OpenAlexW4229333948

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.