Evidence map›Paper›PMID 35617466›Full record

ArticleGlobal spine journal2024

Prognostic Factors for Respiratory Dysfunction for Cervical Spinal Cord Injury and/or Cervical Fractures in Elderly Patients: A Multicenter Survey.

Ryosuke Hirota, Yoshinori Terashima, Hirofumi Ohnishi, Toshihiko Yamashita, Noriaki Yokogawa, Takeshi Sasagawa, Kei Ando, Hiroaki Nakashima, Naoki Segi, Toru Funayama and 52 more

Open access · goldAbstract read
In one paragraph

Article in Global spine journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Danshen (Frontiers in pharmacology · 2026
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

62 authors at 20 institutions in 1 country.

Ryosuke HirotaDepartment of Orthopaedic Surgery, Sapporo Medical University, Sapporo, Japan.ORCID 0000-0002-2210-0497
Yoshinori TerashimaDepartment of Orthopaedic Surgery, Sapporo Medical University, Sapporo, Japan.
Hirofumi OhnishiDepartment of Public Health, Sapporo Medical University, Sapporo, Japan.
Toshihiko YamashitaDepartment of Orthopaedic Surgery, Sapporo Medical University, Sapporo, Japan.
Noriaki YokogawaDepartment of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan.
Takeshi SasagawaDepartment of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan.ORCID 0000-0002-3849-0178
Kei AndoDepartment of Orthopedic Surgery, Graduate School of Medicine, Nagoya University, Nagoya, Japan.ORCID 0000-0002-1088-2903
Hiroaki NakashimaDepartment of Orthopedic Surgery, Graduate School of Medicine, Nagoya University, Nagoya, Japan.ORCID 0000-0002-0039-9678
Naoki SegiDepartment of Orthopedic Surgery, Graduate School of Medicine, Nagoya University, Nagoya, Japan.ORCID 0000-0001-9681-2422
Toru FunayamaDepartment of Orthopaedic Surgery, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
Fumihiko EtoDepartment of Orthopaedic Surgery, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba, Japan.
Akihiro YamajiDepartment of Orthopaedic Surgery, Ibaraki Seinan Medical Center Hospital, Ibaraki, Japan.
Kota WatanabeDepartment of Orthopaedic Surgery, Keio University School of Medicine, Shinjuku-ku, Japan.ORCID 0000-0002-4830-4690
Junichi YamaneDepartment of Orthopaedic Surgery, Keio University School of Medicine, Shinjuku-ku, Japan.
Kazuki TakedaDepartment of Orthopaedic Surgery, Keio University School of Medicine, Shinjuku-ku, Japan.
Takeo FuruyaDepartment of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan.
Atsushi YundeDepartment of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan.
Hideaki NakajimaDepartment of Orthopaedics and Rehabilitation Medicine, Faculty of Medical Sciences University of Fukui, Yoshida-gun, Japan.
Tomohiro YamadaDepartment of Orthopaedic Surgery, Hamamatsu University School of Medicine, Hamamatsu City, Japan.ORCID 0000-0002-7220-7321
Tomohiko HasegawaDepartment of Orthopaedic Surgery, Hamamatsu University School of Medicine, Hamamatsu City, Japan.
Hidenori SuzukiDepartment of Orthopaedic Surgery, Yamaguchi University Graduate School of Medicine, Ube City, Japan.ORCID 0000-0002-3156-0591
Yasuaki ImajoDepartment of Orthopaedic Surgery, Yamaguchi University Graduate School of Medicine, Ube City, Japan.ORCID 0000-0003-1291-745X
Shota IkegamiDepartment of Orthopaedic Surgery, Shinshu University School of Medicine, Matsumoto, Japan.ORCID 0000-0001-6404-5249
Masashi UeharaDepartment of Orthopaedic Surgery, Shinshu University School of Medicine, Matsumoto, Japan.ORCID 0000-0003-0718-6357
Hitoshi TonomuraDepartment of Orthopaedics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Munehiro SakataDepartment of Orthopaedics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Ko HashimotoDepartment of Orthopedic Surgery, Tohoku University Graduate School of Medicine, Sendai, Japan.
Yoshito OnodaDepartment of Orthopedic Surgery, Tohoku University Graduate School of Medicine, Sendai, Japan.
Kenichi KawaguchiDepartment of Orthopedic Surgery, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Yohei HarutaDepartment of Orthopedic Surgery, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Nobuyuki SuzukiDepartment of Orthopedic Surgery, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.
Kenji KatoDepartment of Orthopedic Surgery, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.
Hiroshi UeiDepartment of Orthopedic Surgery, Nihon University Hospital, Chiyoda-ku, Japan.
Hirokatsu SawadaDepartment of Orthopedic Surgery, Nihon University School of Medicine, Itabashi-ku, Japan.
Kazuo NakanishiDepartment of Orthopedics, Traumatology and Spine Surgery, Kawasaki Medical School, Kurashiki, Japan.
Kosuke MisakiDepartment of Orthopedics, Traumatology and Spine Surgery, Kawasaki Medical School, Kurashiki, Japan.
Hidetomi TeraiDepartment of Orthopedic Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan.
Koji TamaiDepartment of Orthopedic Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan.ORCID 0000-0003-1467-2599
Eiki ShirasawaDepartment of Orthopaedic Surgery, Kitasato University School of Medicine, Sagamihara, Japan.
Gen InoueDepartment of Orthopaedic Surgery, Kitasato University School of Medicine, Sagamihara, Japan.ORCID 0000-0001-6500-9004
Kenichiro KakutaniDepartment of Orthopaedic Surgery, Kobe University Graduate School of Medicine, Kobe, Japan.
Yuji KakiuchiDepartment of Orthopaedic Surgery, Kobe University Graduate School of Medicine, Kobe, Japan.
Katsuhito KiyasuDepartment of Orthopaedic Surgery, Kochi Medical School, Kochi University, Nankoku, Japan.
Hiroyuki TominagaDepartment of Orthopaedic Surgery, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan.
Hiroto TokumotoDepartment of Orthopaedic Surgery, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan.
Yoichi IizukaDepartment of Orthopaedic Surgery, Graduate School of Medicine, Gunma University, Maebashi, Japan.
Eiji TakasawaDepartment of Orthopaedic Surgery, Graduate School of Medicine, Gunma University, Maebashi, Japan.
Koji AkedaDepartment of Orthopaedic Surgery, Mie University Graduate School of Medicine, Tsu City, Japan.
Norihiko TakegamiDepartment of Orthopaedic Surgery, Mie University Graduate School of Medicine, Tsu City, Japan.
Haruki FunaoDepartment of Orthopaedic Surgery, School of Medicine, International University of Health and Welfare, Narita, Japan.
Yasushi OshimaDepartment of Orthopaedic Surgery, The University of Tokyo Hospital, Bunkyo-ku, Japan.ORCID 0000-0003-4696-1846
Takashi KaitoDepartment of Orthopaedic Surgery, Osaka University Graduate School of Medicine, Suita, Japan.
Daisuke SakaiDepartment of Orthopedics Surgery, Surgical Science, Tokai University School of Medicine, Isehara, Japan.
Toshitaka YoshiiDepartment of Orthopaedic Surgery, Tokyo Medical and Dental University, Bunkyo-Ku, Japan.ORCID 0000-0003-3511-9020
Tetsuro OhbaDepartment of Orthopaedic Surgery, University of Yamanashi, Chuo, Japan.ORCID 0000-0003-3411-1692
Bungo OtsukiDepartment of Orthopaedic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Shoji SekiDepartment of Orthopaedic Surgery, Faculty of Medicine, University of Toyama, Toyama, Japan.
Masashi MiyazakiDepartment of Orthopaedic Surgery, Faculty of Medicine, Oita University, Oita, Japan.
Masayuki IshiharaDepartment of Orthopaedic Surgery, Kansai Medical University Hospital, Hirakata, Osaka, Japan.ORCID 0000-0001-6062-6767
Seiji OkadaDepartment of Orthopaedic Surgery, Osaka University Graduate School of Medicine, Suita, Japan.
Shiro ImagamaDepartment of Orthopedic Surgery, Graduate School of Medicine, Nagoya University, Nagoya, Japan.ORCID 0000-0002-6951-8575
Satoshi KatoDepartment of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan.
Nagoya University · JPSapporo Medical University · JPKanazawa University · JPKeio University · JPChiba University · JPGunma University · JPHamamatsu University School of Medicine · JPKagoshima University · JPKawasaki Medical School · JPKitasato University · JPKobe University · JPKyoto Prefectural University of Medicine · JPKyushu University · JPMie University · JPNagoya City University · JPNihon University · JPOsaka City University · JPShinshu University · JPThe University of Osaka · JPTohoku University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

designRetrospective Cohort Study.

objectiveThe purpose of this study was to investigate the prognosis of respiratory function in elderly patients with cervical spinal cord injury (SCI) and to identify predictive factors.

methodsWe included 1353 cases of elderly cervical SCI patients collected from 78 institutions in Japan. Patients who required early tracheostomy and ventilator management and those who developed respiratory complications were defined as the respiratory disability group. Patients' background characteristics, injury mechanism, injury form, neurological disability, complications, and treatment methods were compared between the disability and non-disability groups. Multiple logistic regression analysis was used to examine the independent factors. Patients who required respiratory management for 6 months or longer after injury and those who died of respiratory complications were classified into the severe disability group and were compared with minor cases who were weaned off the respirator.

resultsA total of 104 patients (7.8%) had impaired respiratory function. Comparisons between the disabled and non-disabled groups and between the severe and mild injury groups yielded distinct trends. In multiple logistic regression analysis, age, blood glucose level, presence of ossification of posterior longitudinal ligament (OPLL), anterior vertebral hematoma, and critical paralysis were selected as independent risk factors.

conclusionAge, OPLL, severe paralysis, anterior vertebral hematoma, hypoalbuminemia, and blood glucose level at the time of injury were independent factors for respiratory failure. Hyperglycemia may have a negative effect on respiratory function in this condition.

Indexed as

cervical spinal cord injuryhyperglycemiarespiratory dysfunctionrisk factor

Identifiers

PMID35617466
PMCPMC10676156
OpenAlexW4281562434

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.