Evidence map›Paper›PMID 35617055›Full record

ArticleChemical communications (Cambridge, England)2022

Native ambient mass spectrometry of intact protein assemblies directly from

Yuying Du, Robin C May, Helen J Cooper

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemical communications (Cambridge, England), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Yuying DuSchool of Biosciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK. h.j.cooper@bham.ac.uk.ORCID http://orcid.org/0000-0001-7786-0541
Robin C MaySchool of Biosciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK. h.j.cooper@bham.ac.uk.ORCID http://orcid.org/0000-0001-5364-1838
Helen J CooperSchool of Biosciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK. h.j.cooper@bham.ac.uk.ORCID http://orcid.org/0000-0003-4590-9384
University of Birmingham · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Here, we demonstrate that by combining electroporation with native ambient mass spectrometry, it is possible to detect intact non-covalent protein complexes directly from bacterial colonies growing on agar. Homodimers HdeA and HdeB were identified, together with the 50 kDa Mn-bound superoxide dismutase homodimer, in addition to some previously undetected monomeric proteins.

Indexed as

Escherichia coliEscherichia coli ProteinsMass SpectrometryEscherichia coli ProteinshdeA protein, E coli

Identifiers

PMID35617055
PMCPMC9196203
OpenAlexW4282939518

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.