Evidence map›Paper›PMID 35616800›Full record

ReviewMetabolic brain disease2023

Albumin therapy for hepatic encephalopathy: current evidence and controversies.

Yu Jun Wong, Jing Hong Loo

Abstract readReview
PubMed Publisher
In one paragraph

Review in Metabolic brain disease, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. [Research progress on albumin therapy for hepatic encephalopathy].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2024
    Review
  5. Albumin: a comprehensive review and practical guideline for clinical use.European journal of clinical pharmacology · 2024
    Review
  6. Article
  7. Cardiomyopathy in cirrhosis: From pathophysiology to clinical care.JHEP reports : innovation in hepatology · 2024
    Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Yu Jun WongDepartment of Gastroenterology & Hepatology, Changi General Hospital, Singapore, Singapore. wongyujun1985@gmail.com.ORCID http://orcid.org/0000-0002-0727-1183
Jing Hong LooYong Loo Lin School of Medicine, National University of Singapore, Queenstown, Singapore.
National University of Singapore · SGSingHealth · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatic encephalopathy (HE) is a common complication that occurs in 16-21% of end-stage cirrhosis patients. Emerging evidence suggests that systemic inflammation and oxidative stress may play a role in the development of HE. Recent understanding on the anti-inflammatory properties of human albumin has led to growing interest of using human albumin for the treatment and prevention of HE among decompensated patients. In this review, we aim to discuss the current evidence and controversies of using human albumin for the treatment and prevention of HE in advanced cirrhosis patients.

Indexed as

Hepatic EncephalopathyAlbuminsAnti-Inflammatory AgentsHumansLiver CirrhosisSerum Albumin, HumanAlbuminsAnti-Inflammatory AgentsSerum Albumin, HumanAlbuminsHepatic encephalopathyLiver cirrhosisMortality

Identifiers

PMID35616800
OpenAlexW4281555641

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.