Evidence map›Paper›PMID 35616585›Full record

Observational studyAmerican journal of respiratory and critical care medicine2022

Lung Microbiota of Critically Ill Patients with COVID-19 Are Associated with Nonresolving Acute Respiratory Distress Syndrome.

Robert F J Kullberg, Justin de Brabander, Leonoor S Boers, Jason J Biemond, Esther J Nossent, Leo M A Heunks, Alexander P J Vlaar, Peter I Bonta, Tom van der Poll, JanWillem Duitman and 3 more

Open access · hybridAbstract readObservational Study
In one paragraph

Observational study in American journal of respiratory and critical care medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
8.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 62 citations in OpenAlex.

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  10. Pathogens (Basel, Switzerland) · 2025
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 3 countries.

Robert F J KullbergCenter for Experimental and Molecular Medicine.ORCID 0000-0001-8269-9887
Justin de BrabanderCenter for Experimental and Molecular Medicine.
Leonoor S BoersDepartment of Intensive Care Medicine.ORCID 0000-0001-7852-7994
Jason J BiemondCenter for Experimental and Molecular Medicine.
Esther J NossentDepartment of Pulmonary Medicine.
Leo M A HeunksDepartment of Intensive Care Medicine.
Alexander P J VlaarDepartment of Intensive Care Medicine.ORCID 0000-0002-3453-7186
Peter I BontaDepartment of Pulmonary Medicine.
Tom van der PollCenter for Experimental and Molecular Medicine.
JanWillem DuitmanDepartment of Pulmonary Medicine.
Lieuwe D J BosDepartment of Intensive Care Medicine.
W Joost WiersingaCenter for Experimental and Molecular Medicine.
ArtDECO Consortium and the Amsterdam UMC COVID-19 Biobank Study Group
Center for Molecular Medicine and Immunology · USIntensive Care Society · GBOffice of Infectious Diseases · USPulmonary Associates · USAmsterdam University Medical Centers · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

COVID-19MicrobiotaRespiratory Distress SyndromeCritical IllnessHumansLungRespiration, ArtificialRNA, Ribosomal, 16STumor Necrosis Factor-alphaRNA, Ribosomal, 16STumor Necrosis Factor-alphaartificial respirationcritical illnesshost–microbial interactionslung microbiome

Identifiers

PMID35616585
PMCPMC9799265
OpenAlexW4281561573

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.