ArticleNeurorehabilitation and neural repair2022
Baseline Predictors of Response to Repetitive Task Practice in Chronic Stroke.
Article in Neurorehabilitation and neural repair, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 16 citations in OpenAlex.
- Virtual Reality-Assisted Rehabilitation for Upper-Limb Function in Stroke Survivors: A Systematic Review.Brain sciences · 2026Review
- Machine learning-based study of the predictors of clinically important change in patient-reported outcomes in bilateral upper-limb function in patients receiving robotic stroke rehabilitation.Frontiers in rehabilitation sciences · 2026Article
- Multidimensional feature analysis shows stratification in robotic-motor-training gains based on the level of pre-training motor impairment in stroke.Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference · 2024Article
- Improvements in motor control are associated with improved quality of life following an at-home muscle biofeedback program for chronic stroke.Frontiers in human neuroscience · 2024Article
- Opportunities and challenges in the development of exoskeletons for locomotor assistance.Nature biomedical engineering · 2023Review
- Article
- Prediction of rehabilitation induced motor recovery after stroke using a multi-dimensional and multi-modal approach.Frontiers in aging neuroscience · 2023Article
- Considerations for at-home upper-limb rehabilitation technology following stroke: Perspectives of stroke survivors and therapists.Journal of rehabilitation and assistive technologies engineeringArticle
Corrections and comments
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Authors and funding
12 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundRepetitive task practice reduces mean upper extremity motor impairment in
objectivesTo identify prognostic factors and better understand the biological substrate for reductions in arm impairment in response to repetitive task practice among patients with chronic (≥6 months) post-stroke hemiparesis.
methodsThe intervention is a form of repetitive task practice using a combination of robot-assisted therapy and functional arm use in real-world tasks. Baseline measures include the Fugl-Meyer Assessment, Wolf Motor Function Test, Action Research Arm Test, Stroke Impact Scale, questionnaires on pain and expectancy, MRI, transcranial magnetic stimulation, kinematics, accelerometry, and genomic testing.
resultsMean increase in FM-UE was 4.6 ± 1.0 SE, median 2.5. Approximately one-third of participants had a clinically meaningful response to the intervention, defined as an increase in FM ≥ 5. The selected logistic regression model had a receiver operating curve with AUC = .988 (Std Error = .011, 95% Wald confidence limits: .967-1) showed little evidence of overfitting. Six variables that predicted response represented impairment, functional, and genomic measures.
conclusionA simple weighted sum of 6 baseline factors can accurately predict clinically meaningful impairment reduction after outpatient intensive practice intervention in chronic stroke. Reduction of impairment may be a critical first step to functional improvement. Further validation and generalization of this model will increase its utility in clinical decision-making.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.