ArticleJournal of the Royal Society of Medicine2022
The role of systematic reviews in identifying the limitations of preclinical animal research, 2000-2022: part 2.
Article in Journal of the Royal Society of Medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- A Systematic Review of Stem Cell Secretome-Derived Exosomes for Neuropathic Pain: Therapeutic Mechanisms and Translational Potential.Molecular neurobiology · 2026Pooled it
- Neuroprotective effects and mechanistic insights of sinomenine in ischemic stroke: a systematic review and meta-analysis of preclinical animal studies.Frontiers in pharmacology · 2026Pooled it
- A sociological perspective on the challenges of displacing animal research within academia: the contribution of Bourdieu.NAM journal · 2025Article
- Use and reporting of systematic review methodology in EFSA scientific opinions on animal health and welfare.Frontiers in veterinary science · 2025Article
- Toward a roadmap for addressing today's health dilemma-The 101-statement consensus report.Frontiers in nutrition · 2025Article
- Value of preclinical systematic reviews and meta-analyses in pediatric research.Pediatric research · 2024Article
- Advancing the 3Rs: innovation, implementation, ethics and society.Frontiers in veterinary science · 2023Article
- Workforce, workforce, workforce: a wellbeing crisis without resolution.Journal of the Royal Society of Medicine · 2022Article
- Mitigating animal methods bias to reduce animal use and improve biomedical translation.Science progressArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.