Evidence map›Paper›PMID 35616244›Full record

ArticleNanoscale2022

Measuring the refractive index and sub-nanometre surface functionalisation of nanoparticles in suspension.

Niall M C Mulkerns, William H Hoffmann, Javier Ramos-Soriano, Noelia de la Cruz, Teodoro Garcia-Millan, Robert L Harniman, Ian D Lindsay, Annela M Seddon, M Carmen Galan, Henkjan Gersen

Abstract read
In one paragraph

Article in Nanoscale, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Niall M C MulkernsH. H. Wills Physics Laboratory, University of Bristol, Bristol, BS8 1TL, UK. h.gersen@bristol.ac.uk.ORCID http://orcid.org/0000-0002-7839-5896
William H HoffmannH. H. Wills Physics Laboratory, University of Bristol, Bristol, BS8 1TL, UK. h.gersen@bristol.ac.uk.ORCID http://orcid.org/0000-0002-6689-2609
Javier Ramos-SorianoSchool of Chemistry, University of Bristol, Bristol, BS8 1TS, UK.ORCID http://orcid.org/0000-0002-3054-0679
Noelia de la CruzSchool of Chemistry, University of Bristol, Bristol, BS8 1TS, UK.ORCID http://orcid.org/0000-0002-9917-1234
Teodoro Garcia-MillanBristol Centre for Functional Nanomaterials, University of Bristol, Bristol, BS8 1TL, UK.
Robert L HarnimanSchool of Chemistry, University of Bristol, Bristol, BS8 1TS, UK.ORCID http://orcid.org/0000-0002-3452-1213
Ian D LindsayH. H. Wills Physics Laboratory, University of Bristol, Bristol, BS8 1TL, UK. h.gersen@bristol.ac.uk.
Annela M SeddonH. H. Wills Physics Laboratory, University of Bristol, Bristol, BS8 1TL, UK. h.gersen@bristol.ac.uk.ORCID http://orcid.org/0000-0002-5794-8500
M Carmen GalanSchool of Chemistry, University of Bristol, Bristol, BS8 1TS, UK.ORCID http://orcid.org/0000-0001-7307-2871
Henkjan GersenH. H. Wills Physics Laboratory, University of Bristol, Bristol, BS8 1TL, UK. h.gersen@bristol.ac.uk.ORCID http://orcid.org/0000-0002-9253-7555

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Direct measurements to determine the degree of surface coverage of nanoparticles by functional moieties are rare, with current strategies requiring a high level of expertise and expensive equipment. Here, a practical method to determine the ratio of the volume of the functionalisation layer to the particle volume based on measuring the refractive index of nanoparticles in suspension is proposed. As a proof of concept, this technique is applied to poly(methyl methacrylate) (PMMA) nanoparticles and semicrystalline carbon dots functionalised with different surface moieties, yielding refractive indices that are commensurate to those from previous literature and Mie theory. In doing so, it is demonstrated that this technique is able to optically detect differences in surface functionalisation or composition of nanometre-sized particles. This non-destructive and rapid method is well-suited for

Identifiers

PMID35616244
PMCPMC9178438

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.