Evidence map›Paper›PMID 35615882›Full record

ArticleThe journal of histochemistry and cytochemistry : official journal of the Histochemistry Society2022

GLUT1, LDHA, and MCT4 Expression Is Deregulated in Cervical Cancer and Precursor Lesions.

Ma A Reyna-Hernández, Luz Del C Alarcón-Romero, Julio Ortiz-Ortiz, Berenice Illades-Aguiar, Marco A Jiménez-López, Azucena Ocampo-Bárcenas, Martin O Morrugares-Ixtepan, Francisco I Torres-Rojas

Open access · bronzeAbstract read
In one paragraph

Article in The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 30 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Ma A Reyna-HernándezLaboratorio de Citopatología e Histoquímica, Instituto Estatal de Cancerología "Dr. Arturo Beltrán Ortega," Acapulco de Juárez, México.
Luz Del C Alarcón-RomeroLaboratorio de Citopatología e Histoquímica, Instituto Estatal de Cancerología "Dr. Arturo Beltrán Ortega," Acapulco de Juárez, México.ORCID 0000-0002-2074-4889
Julio Ortiz-OrtizLaboratorio de Biomedicina Molecular, Instituto Estatal de Cancerología "Dr. Arturo Beltrán Ortega," Acapulco de Juárez, México.
Berenice Illades-AguiarLaboratorio de Biomedicina Molecular, Instituto Estatal de Cancerología "Dr. Arturo Beltrán Ortega," Acapulco de Juárez, México.
Marco A Jiménez-LópezFacultad de Ciencias Químico-Biológicas, Universidad Autónoma de Guerrero, Chilpancingo de los Bravo, México, and Anatomía Patológica, Instituto Estatal de Cancerología "Dr. Arturo Beltrán Ortega," Acapulco de Juárez, México.
Azucena Ocampo-BárcenasLaboratorio de Patología Molecular, Instituto Estatal de Cancerología "Dr. Arturo Beltrán Ortega," Acapulco de Juárez, México.
Martin O Morrugares-IxtepanFacultad de Ciencias Químico-Biológicas, Universidad Autónoma de Guerrero, Chilpancingo de los Bravo, México, and Anatomía Patológica, Instituto Estatal de Cancerología "Dr. Arturo Beltrán Ortega," Acapulco de Juárez, México.
Francisco I Torres-RojasLaboratorio de Biomedicina Molecular, Instituto Estatal de Cancerología "Dr. Arturo Beltrán Ortega," Acapulco de Juárez, México.ORCID 0000-0003-4303-8677
Universidad Autónoma de Guerrero · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metabolic reprogramming is typical in cancerous cells and is required for proliferation and cellular survival. In addition, oncoproteins of high-risk human papillomavirus (HR-HPV) are involved in this process. This study evaluated the relationship between glucose transporter I (GLUT1), lactate dehydrogenase A (LDHA), and monocarboxylate transporter type 4 (MCT4) expression and cervical intraepithelial neoplasia (CIN) and invasive cervical carcinoma (ICC) with HR-HPV infection. The protein expression was evaluated in women with CIN I (

Indexed as

Papillomavirus InfectionsUterine Cervical DysplasiaUterine Cervical NeoplasmsFemaleGlucose Transporter Type 1Glucose Transport Proteins, FacilitativeHumansLactate Dehydrogenase 5L-Lactate DehydrogenaseMonocarboxylic Acid TransportersMuscle ProteinsGlucose Transporter Type 1Glucose Transport Proteins, FacilitativeLactate Dehydrogenase 5LDHA protein, humanL-Lactate DehydrogenaseMonocarboxylic Acid TransportersMuscle ProteinsSLC16A4 protein, humanSLC2A1 protein, humanaltered expressionbiomarker prognosiscervical cancerHPV

Identifiers

PMID35615882
PMCPMC9169107
OpenAlexW4281570306

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.