Evidence map›Paper›PMID 35615739›Full record

ArticleFrontiers in molecular biosciences2022

Molecular Mingling: Multimodal Predictions of Ligand Promiscuity in Pentameric Ligand-Gated Ion Channels.

Filip Koniuszewski, Florian D Vogel, Konstantina Bampali, Jure Fabjan, Thomas Seidel, Petra Scholze, Philip B Schmiedhofer, Thierry Langer, Margot Ernst

Open access · goldAbstract read
In one paragraph

Article in Frontiers in molecular biosciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Cys-loop receptors on cannabinoids: All high?Frontiers in physiology · 2022
    Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Filip KoniuszewskiDepartment of Pathobiology of the Nervous System, Center for Brain Research, Medical University Vienna, Vienna, Austria.
Florian D VogelDepartment of Pathobiology of the Nervous System, Center for Brain Research, Medical University Vienna, Vienna, Austria.
Konstantina BampaliDepartment of Pathobiology of the Nervous System, Center for Brain Research, Medical University Vienna, Vienna, Austria.
Jure FabjanDepartment of Pathobiology of the Nervous System, Center for Brain Research, Medical University Vienna, Vienna, Austria.
Thomas SeidelDepartment of Pharmaceutical Sciences, Division of Pharmaceutical Chemistry, University of Vienna, Vienna, Austria.
Petra ScholzeDepartment of Pathobiology of the Nervous System, Center for Brain Research, Medical University Vienna, Vienna, Austria.
Philip B SchmiedhoferDepartment of Pathobiology of the Nervous System, Center for Brain Research, Medical University Vienna, Vienna, Austria.
Thierry LangerDepartment of Pharmaceutical Sciences, Division of Pharmaceutical Chemistry, University of Vienna, Vienna, Austria.
Margot ErnstDepartment of Pathobiology of the Nervous System, Center for Brain Research, Medical University Vienna, Vienna, Austria.
Medical University of Vienna · ATUniversity of Vienna · AT

Funding

Austrian Science Fund FWF DOC 33Austrian Science Fund FWF W 1232
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

allosteric ligandscys-loop receptorsneuropsychiatric adverse eventspentameric ligand-gated ion channelsprotein-ligand interactions

Identifiers

PMID35615739
PMCPMC9124788
OpenAlexW4229372435

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.