Evidence map›Paper›PMID 35615582›Full record

ArticlePEARC20 : Practice and Experience in Advanced Research Computing 2020 : Catch the wave : July 27-31, 2020, Portland, Or Virtual Conference. Practice and Experience in Advanced Research Computing (Conference) (2020 : Online)2020

TopPIC Gateway: A Web Gateway for Top-Down Mass Spectrometry Data Interpretation.

In Kwon Choi, Eroma Abeysinghe, Eric Coulter, Suresh Marru, Marlon Pierce, Xiaowen Liu

Abstract read
In one paragraph

Article in PEARC20 : Practice and Experience in Advanced Research Computing 2020 : Catch the wave : July 27-31, 2020, Portland, Or Virtual Conference. Practice and Experience in Advanced Research Computing (Conference) (2020 : Online), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

In Kwon ChoiDepartment of BioHealth Informatics, Indiana University-Purdue University Indianapolis.
Eroma AbeysingheCyberinfrastructure Integration Research Center, Indiana University.
Eric CoulterCyberinfrastructure Integration Research Center, Indiana University.
Suresh MarruCyberinfrastructure Integration Research Center, Indiana University.
Marlon PierceCyberinfrastructure Integration Research Center, Indiana University.
Xiaowen LiuDepartment of BioHealth Informatics, Indiana University-Purdue University Indianapolis.

Funding

Structural Biology CoreU54AG065181 · NIA · INDIANA UNIVERSITY INDIANAPOLIS · PI Timothy I Richardson · 2019 to 2026
$61.3M
Computational tools for top down mass spectrometry based proteoform identification and proteogenomicsR01GM118470 · NIGMS · TULANE UNIVERSITY OF LOUISIANA · PI Xiaowen Liu · 2016 to 2026
$2.7M
NIA NIH HHS U54 AG065181NIGMS NIH HHS R01 GM118470
6 · The paper itself

Abstract

Top-down mass spectrometry-based proteomics has become the method of choice for identifying and quantifying intact proteoforms in biological samples. We present a web-based gateway for TopPIC suite, a widely used software suite consisting of four software tools for top-down mass spectrometry data interpretation: TopFD, TopPIC, TopMG, and TopDiff. The gateway enables the community to use heterogeneous collection of computing resources that includes high performance computing clusters at Indiana University and virtual clusters on XSEDE's Jetstream Cloud resource for top-down mass spectral data analysis using TopPIC suite. The gateway will be a useful resource for proteomics researchers and students who have limited access to high-performance computing resources or who are not familiar with interacting with server-side supercomputers.

Indexed as

Apache AiravataApplied computing → BioinformaticsInformation systems → Computing platformsProteomicsScience GatewaysSciGaPTop-down mass spectrometryXSEDE

Identifiers

PMID35615582
PMCPMC9128478

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.