Evidence map›Paper›PMID 35615559›Full record

ArticleFrontiers in cardiovascular medicine2022

Percutaneous Coronary Intervention vs. Coronary Artery Bypass Grafting for Treating In-Stent Restenosis in Unprotected-Left Main: LM-DRAGON-Registry.

Wojciech Wańha, Jacek Bil, Michalina Kołodziejczak, Adam Kowalówka, Mariusz Kowalewski, Damian Hudziak, Radosław Gocoł, Rafał Januszek, Tomasz Figatowski, Marek Milewski and 35 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04968977 (Long-term Outcomes Following Percutaneous Coronary Intervention Versus Coronary Artery Bypass Grafting for Treating In-stent Restenosis in Unprotected Left Main Coronary Artery), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04968977 completednot on this map

Long-term Outcomes Following Percutaneous Coronary Intervention Versus Coronary Artery Bypass Grafting for Treating In-stent Restenosis in Unprotected Left Main Coronary Artery: Multicenter LM-DRAGON Registry

Typeobservational_patient_registrySponsorMedical University of SilesiaRan2001 to 2021Enrolled305ConditionsRestenosis, Coronary, Left Main Coronary Artery Disease, PTCA Left Main Artery ComplicationsArmsPCI vs. CABG
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

45 authors at 14 institutions in 5 countries.

Wojciech WańhaDepartment of Cardiology and Structural Heart Diseases, Medical University of Silesia, Katowice, Poland.
Jacek BilDepartment of Invasive Cardiology, Centre of Postgraduate Medical Education, Warsaw, Poland.
Michalina KołodziejczakDepartment of Anaesthesiology and Intensive Care, Ludwik Rydygier Collegium Medicum, Nicolaus Copernicus University, Antoni Jurasz University Hospital No. 1, Bydgoszcz, Poland.
Adam KowalówkaDepartment of Cardiac Surgery, Medical University of Silesia, Katowice, Poland.
Mariusz KowalewskiDepartment of Cardiac Surgery, Central Clinical Hospital of the Ministry of Interior, Centre of Postgraduate Medical Education, Warsaw, Poland.
Damian HudziakDepartment of Cardiac Surgery, Medical University of Silesia, Katowice, Poland.
Radosław GocołDepartment of Cardiac Surgery, Medical University of Silesia, Katowice, Poland.
Rafał JanuszekDepartment of Cardiology, Jagiellonian University Medical College, Krakow, Poland.
Tomasz FigatowskiFirst Department of Cardiology, Medical University of Gdansk, Gdansk, Poland.
Marek MilewskiDepartment of Cardiology and Structural Heart Diseases, Medical University of Silesia, Katowice, Poland.
Brunon TomasiewiczDepartment of Heart Disease, Centre for Heart Disease, University Hospital Wroclaw, Wroclaw Medical University, Wrocław, Poland.
Piotr KüblerDepartment of Heart Disease, Centre for Heart Disease, University Hospital Wroclaw, Wroclaw Medical University, Wrocław, Poland.
Bruno HrymniakDepartment of Heart Disease, Centre for Heart Disease, University Hospital Wroclaw, Wroclaw Medical University, Wrocław, Poland.
Piotr DesperakThird Department of Cardiology, Medical University of Silesia, Zabrze, Poland.
Łukasz KuźmaDepartment of Invasive Cardiology, Medical University of Bialystok, Białystok, Poland.
Krzysztof MilewskiCenter for Cardiovascular Research and Development, American Heart of Poland, Katowice, Poland.
Bartłomiej GóraCenter for Cardiovascular Research and Development, American Heart of Poland, Katowice, Poland.
Andrzej ŁośDepartment of Cardiac and Vascular Surgery, Medical University of Gdansk, Gdansk, Poland.
Jan KulczyckiDepartment of Cardiology, Miedziowe Centrum Zdrowia, Lubin, Poland.
Adrian WłodarczakDepartment of Cardiology, Miedziowe Centrum Zdrowia, Lubin, Poland.
Wojciech SkorupskiDepartment of Cardiology, Poznan University of Medical Sciences, Poznań, Poland.
Marek GrygierDepartment of Cardiology, Poznan University of Medical Sciences, Poznań, Poland.
Maciej LesiakDepartment of Cardiology, Poznan University of Medical Sciences, Poznań, Poland.
Fabrizio D'AscenzoDivision of Cardiology, Department of Internal Medicine, Città della Salute e della Scienza, University of Turin, Turin, Italy.
Marek AndresDepartment of Interventional Cardiology, Jagiellonian University Medical College Institute of Cardiology, John Paul II Hospital, Krakow, Poland.
Paweł KleczynskiDepartment of Interventional Cardiology, Jagiellonian University Medical College Institute of Cardiology, John Paul II Hospital, Krakow, Poland.
Radosław LitwinowiczDepartment of Cardiovascular Surgery and Transplantology, Jagiellonian University, John Paul II Hospital, Krakow, Poland.
Andrea BorinDivision of Cardiology, Department of Internal Medicine, Città della Salute e della Scienza, University of Turin, Turin, Italy.
Grzegorz SmolkaDepartment of Cardiology and Structural Heart Diseases, Medical University of Silesia, Katowice, Poland.
Krzysztof ReczuchDepartment of Heart Disease, Centre for Heart Disease, University Hospital Wroclaw, Wroclaw Medical University, Wrocław, Poland.
Marcin GruchałaFirst Department of Cardiology, Medical University of Gdansk, Gdansk, Poland.
Robert J GilDepartment of Invasive Cardiology, Centre of Postgraduate Medical Education, Warsaw, Poland.
Miłosz JaguszewskiFirst Department of Cardiology, Medical University of Gdansk, Gdansk, Poland.
Krzysztof BartuśDepartment of Cardiovascular Surgery and Transplantology, Jagiellonian University, John Paul II Hospital, Krakow, Poland.
Piotr SuwalskiDepartment of Cardiac Surgery, Central Clinical Hospital of the Ministry of Interior, Centre of Postgraduate Medical Education, Warsaw, Poland.
Sławomir DobrzyckiDepartment of Invasive Cardiology, Medical University of Bialystok, Białystok, Poland.
Dariusz DudekDepartment of Cardiology, Jagiellonian University Medical College, Krakow, Poland.
Stanisław BartuśDepartment of Cardiology, Jagiellonian University Medical College, Krakow, Poland.
Mariusz Ga SiorThird Department of Cardiology, Medical University of Silesia, Zabrze, Poland.
Andrzej OchałaDepartment of Cardiology and Structural Heart Diseases, Medical University of Silesia, Katowice, Poland.
Alexandra J LanskyYale University School of Medicine, New Haven, CT, United States.
Marek DejaDepartment of Cardiac Surgery, Medical University of Silesia, Katowice, Poland.
Jacek LegutkoDepartment of Interventional Cardiology, Jagiellonian University Medical College Institute of Cardiology, John Paul II Hospital, Krakow, Poland.
Elvin KedhiDepartment of Cardiology and Structural Heart Diseases, Medical University of Silesia, Katowice, Poland.
Wojciech WojakowskiDepartment of Cardiology and Structural Heart Diseases, Medical University of Silesia, Katowice, Poland.
Medical University of Silesia · PLJohn Paul II Hospital · PLGdańsk Medical University · PLWroclaw Medical University · PLJagiellonian University · PLPoznan University of Medical Sciences · PLAmerican Heart of Poland · PLMedical University of Białystok · PLPostgraduate School of Molecular Medicine · PLUniversity of Turin · ITAntoni Jurasz University Hospital · PLCentral Clinical Hospital · PLNicolaus Copernicus University · PLYale University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Data regarding management of patients with unprotected left main coronary artery in-stent restenosis (LM-ISR) are scarce. Objectives: This study investigated the safety and effectiveness of percutaneous coronary intervention (PCI) vs. coronary artery bypass grafting (CABG) for the treatment of unprotected LM-ISR. Methods: Consecutive patients who underwent PCI or CABG for unprotected LM-ISR were enrolled. The primary endpoint was a composite of major adverse cardiac and cerebrovascular events (MACCE), defined as cardiac death, myocardial infarction (MI), target vessel revascularization (TVR), and stroke. Results: A total of 305 patients were enrolled, of which 203(66.6%) underwent PCI and 102(33.4%) underwent CABG. At 30-day follow-up, a lower risk of cardiac death was observed in the PCI group, compared with the CABG-treated group (2.1% vs. 7.1%, Conclusions: This analysis of patients with LM-ISR revealed a lower incidence of cardiac death in PCI compared with CABG in short-term follow-up. During the long-term follow-up, no differences in MACCE were observed, but patients treated with CABG less often required TVR. Visual overview: A visual overview is available for this article. Registration: https://www.clinicaltrials.gov; Unique identifier: NCT04968977.

Indexed as

coronary artery bypass graft (CABG)in-stent restenosis (ISR)left mainpercutaneous coronary intervention (complex PCI)stents (Coronary)

Identifiers

PMID35615559
PMCPMC9125786
OpenAlexW4225156926

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.