Evidence map›Paper›PMID 35615518›Full record

ArticleFrontiers in microbiology2022

Mutational Switch-Backs Can Accelerate Evolution of

Heer H Mehta, David Ibarra, Christopher J Marx, Craig R Miller, Yousif Shamoo

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Intracellular Experimental Evolution ofACS infectious diseases · 2023
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Heer H MehtaDepartment of Biosciences, Rice University, Houston, TX, United States.
David IbarraDepartment of Biosciences, Rice University, Houston, TX, United States.
Christopher J MarxDepartment of Biological Sciences, University of Idaho, Moscow, ID, United States.
Craig R MillerDepartment of Biological Sciences, University of Idaho, Moscow, ID, United States.
Yousif ShamooDepartment of Biosciences, Rice University, Houston, TX, United States.
Rice University · USUniversity of Idaho · US

Funding

Sequence-structure-function relationships in human visual photopigmentsP20GM104420 · NIGMS · UNIVERSITY OF IDAHO · PI VAN LEUVEN, JAMES · 2015 to 2024
$22.9M
Defining Evolutionary Trajectories: Molecular adaptation to antibiotic resistanceR01AI080714 · NIAID · RICE UNIVERSITY · PI SHAMOO, YOUSIF · 2009 to 2023
$4.3M
NIAID NIH HHS R01 AI080714NIGMS NIH HHS P20 GM104420
6 · The paper itself

Abstract

Combination antimicrobial therapy has been considered a promising strategy to combat the evolution of antimicrobial resistance.

Indexed as

antibiotic combinationexperimental evolutionFrancisellamutational switch-backswhole genome sequencing

Identifiers

PMID35615518
PMCPMC9125183
OpenAlexW4229367341

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.