Evidence map›Paper›PMID 35615409›Full record

ArticlePaediatrics & child health2022

Mental health profiles of autistic children and youth during the COVID-19 pandemic.

Marina Charalampopoulou, Eun Jung Choi, Daphne J Korczak, Katherine T Cost, Jennifer Crosbie, Catherine S Birken, Alice Charach, Suneeta Monga, Elizabeth Kelley, Rob Nicolson and 5 more

Open access · bronzeAbstract read
In one paragraph

Article in Paediatrics & child health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 1 country.

Marina CharalampopoulouHolland Bloorview Research Institute, Toronto, Ontario, Canada.
Eun Jung ChoiHolland Bloorview Research Institute, Toronto, Ontario, Canada.
Daphne J KorczakDepartment of Psychiatry, Hospital for Sick Children, Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0002-0061-7495
Katherine T CostDepartment of Psychiatry, Hospital for Sick Children, Toronto, Ontario, Canada.
Jennifer CrosbieDepartment of Psychiatry, Hospital for Sick Children, Toronto, Ontario, Canada.
Catherine S BirkenDepartment of Pediatrics, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0003-0308-8645
Alice CharachDepartment of Psychiatry, Hospital for Sick Children, Toronto, Ontario, Canada.
Suneeta MongaDepartment of Psychiatry, Hospital for Sick Children, Toronto, Ontario, Canada.
Elizabeth KelleyDepartment of Psychology, Queen's University, Kingston, Ontario, Canada.
Rob NicolsonDepartment of Psychiatry, Western University, London, Ontario, Canada.
Stelios GeorgiadesDepartment of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, Ontario, Canada.
Muhammad AyubDepartment of Psychiatry, Queen's University, Kingston, Ontario, Canada.
Russell J SchacharDepartment of Psychiatry, Hospital for Sick Children, Toronto, Ontario, Canada.
Alana IaboniHolland Bloorview Research Institute, Toronto, Ontario, Canada.
Evdokia AnagnostouHolland Bloorview Research Institute, Toronto, Ontario, Canada.
University of Toronto · CAHolland Bloorview Kids Rehabilitation Hospital · CAQueen's University · CAHospital for Sick Children · CAMcMaster University · CAWestern University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Canadian province-wide lockdowns have challenged children's mental health (MH) during the COVID-19 pandemic, with autistic children being at particular risk. The purpose of our study was to identify sub-groups of autistic children with distinct mental health change profiles, to understand the child-, parent-, and system-specific factors associated with such profiles in order to ultimately inform future interventions. Methods: Data were drawn from a large Canadian cohort (N=1,570) across Ontario, resulting in 265 autistic children (mean age=10.9 years, 76% male). K-means clustering analyses were employed to partition distinct MH profiles in six MH measures (mood, anxiety, OCD symptoms, irritability, inattention, hyperactivity) and group differences were examined with reference to the above factors. Additionally, we investigated the characteristics of children who accessed acute MH services. Results: The optimal number of clusters was two; one included those experiencing MH deterioration across all six MH measures (61.3%, 95% confidence interval [CI]=54.9 to 67.4), and a second included youth that did not experience MH changes (38.7%, 95%CI=32.6 to 45.1). Child-specific factors associated with MH deterioration included higher pre-existing internalizing symptoms, high levels of COVID stress. Parental MH challenges and system-specific factors, such as the loss of learning supports, access to physicians and material deprivation, were also associated with MH deterioration. Access to acute MH services were primarily associated with financial insecurity and loss of services. Conclusions: More than half of autistic children experienced MH deterioration, and person-specific (pre-existing MH, COVID related stress), parent-specific (Parent MH) and system-level (loss of services and material deprivation) characteristics were associated with such decline, providing clinical and policy opportunities for intervention at multiple levels.

Indexed as

AutismChildrenCOVIDMental healthPandemic

Identifiers

PMID35615409
PMCPMC9126276
OpenAlexW4229000742

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.