Evidence map›Paper›PMID 35615258›Full record

ArticleJournal of diabetes research2022

Variability in Test Interval Is Linked to Glycated Haemoglobin (HbA1c) Trajectory over Time.

Anthony A Fryer, David Holland, Michael Stedman, Christopher J Duff, Lewis Green, Jonathan Scargill, Fahmy W F Hanna, Pensée Wu, R John Pemberton, Christine Bloor and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of diabetes research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. The Effect of the COVID-19 Pandemic on HbA1c Testing: Prioritization of High-Risk Cases and Impact of Social Deprivation.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 1 country.

Anthony A FryerSchool of Medicine, Keele University, Keele, Staffordshire, UK.ORCID https://orcid.org/0000-0001-8678-0404
David HollandThe Benchmarking Partnership, Alsager, Cheshire, UK.
Michael StedmanRes Consortium, Andover, UK.ORCID https://orcid.org/0000-0002-0491-7823
Christopher J DuffSchool of Medicine, Keele University, Keele, Staffordshire, UK.ORCID https://orcid.org/0000-0002-3753-0043
Lewis GreenDepartment of Clinical Biochemistry, St. Helens & Knowsley Teaching Hospitals NHS Trust, Whiston Hospital, Prescot, UK.ORCID https://orcid.org/0000-0001-5792-5408
Jonathan ScargillDepartment of Clinical Biochemistry, The Royal Oldham Hospital, The Northern Care Alliance NHS Group, Oldham, UK.
Fahmy W F HannaDepartment of Diabetes and Endocrinology, University Hospitals of North Midlands NHS Trust, Stoke-on-Trent, Staffordshire, UK.ORCID https://orcid.org/0000-0001-5800-1442
Pensée WuSchool of Medicine, Keele University, Keele, Staffordshire, UK.ORCID https://orcid.org/0000-0003-0011-5636
R John PembertonDiabetes UK (North Staffordshire Branch), Porthill, Stoke-on-Trent, Staffordshire, UK.
Christine BloorDiabetes UK (North Staffordshire Branch), Porthill, Stoke-on-Trent, Staffordshire, UK.
Adrian H HealdDepartment of Diabetes and Endocrinology, Salford Royal NHS Foundation Trust, Salford, UK.ORCID https://orcid.org/0000-0002-9537-4050
University Hospitals of North Midlands NHS Trust · GBDiabetes UK · GBBenchmark (United Kingdom) · GBManchester Academic Health Science Centre · GBRoyal Oldham Hospital · GBSt Helens and Knowsley Teaching Hospitals NHS Trust · GBUniversity of Staffordshire · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aims: We previously showed that the glycated haemoglobin (HbA1c) testing frequency links to diabetes control. Here, we examine the effect of variability in test interval, adjusted for the frequency, on change in HbA1c ( Results: In general, less variability in testing frequency (more consistent monitoring) was associated with better diabetes control. This was most evident with moderately raised baseline HbA1c levels (7.0-9.0% (54-75 mmol/mol)). For example, in those with a starting HbA1c of 7.0-7.5% (54-58 mmol/mol), the lowest SD decile was associated with little change in HbA1c over 5 years, while for those with the highest decile, HbA1c rose by 0.4-0.6% (4-6 mmol/mol; Conclusions: These findings indicate that the consistency of testing interval, not the just number of tests/year, is important in maintaining diabetes control, especially in those with moderately raised HbA1c levels. Systems to improve regularity of HbA1c testing are therefore needed, especially given the impact of COVID-19 on diabetes monitoring.

Indexed as

Diabetes Mellitus, Type 2Glycated HemoglobinHumansMultivariate AnalysisReproducibility of ResultsGlycated Hemoglobin

Identifiers

PMID35615258
PMCPMC9126657
OpenAlexW4280551520

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.