Evidence map›Paper›PMID 35615235›Full record

ArticleJournal of the Intensive Care Society2022

Outcomes of critically ill COVID-19 patients managed in a high-volume severe respiratory failure and ECMO centre in the United Kingdom.

Peter B Sherren, Luigi Camporota, Barnaby Sanderson, Andrew Jones, Manu Shankar-Hari, Chris Is Meadows, Nicholas Barrett, Marlies Ostermann, Nicholas Hart

Abstract read
In one paragraph

Article in Journal of the Intensive Care Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Peter B SherrenDepartment of Critical Care Medicine, Guy's and St Thomas' NHS Foundation Trust, London, UK.ORCID https://orcid.org/0000-0003-3885-0564
Luigi CamporotaDepartment of Critical Care Medicine, Guy's and St Thomas' NHS Foundation Trust, London, UK.ORCID https://orcid.org/0000-0001-5600-1676
Barnaby SandersonDepartment of Critical Care Medicine, Guy's and St Thomas' NHS Foundation Trust, London, UK.ORCID https://orcid.org/0000-0002-9621-143X
Andrew JonesDepartment of Critical Care Medicine, Guy's and St Thomas' NHS Foundation Trust, London, UK.
Manu Shankar-HariDepartment of Critical Care Medicine, Guy's and St Thomas' NHS Foundation Trust, London, UK.
Chris Is MeadowsDepartment of Critical Care Medicine, Guy's and St Thomas' NHS Foundation Trust, London, UK.
Nicholas BarrettDepartment of Critical Care Medicine, Guy's and St Thomas' NHS Foundation Trust, London, UK.ORCID https://orcid.org/0000-0002-4641-8192
Marlies OstermannDepartment of Critical Care Medicine, Guy's and St Thomas' NHS Foundation Trust, London, UK.
Nicholas HartDepartment of Critical Care Medicine, Guy's and St Thomas' NHS Foundation Trust, London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During the Coronavirus Disease 2019 (COVID-19) pandemic institutions have needed to develop pragmatic clinical pathways to balance the excess critical care demand and local resources. In this single-centre retrospective cohort study we describe the outcomes of COVID-19 patients admitted to Guy's and St. Thomas' NHS Foundation Trust (GSTT) critical care service. Patients were managed according to a local respiratory failure management pathway that was predicated on timely invasive ventilation when indicated and tailored ventilatory strategies according to pulmonary mechanics. Between 2 March and 25 May 2020 GSTT critical care service admitted 316 patients with confirmed COVID-19. Of the 201 patients admitted directly through the Emergency Department (ED) with a completed critical care outcome, 71.1% survived to critical care discharge. These favourable outcomes may serve to inform the wider debate on optimal organ support in COVID-19.

Indexed as

ARDSCOVID-19respiratory failureSARS-CoV-2ventilation

Identifiers

PMID35615235
PMCPMC9125444

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.