Evidence map›Paper›PMID 35615112›Full record

ArticleBrain communications2022

Vestibular/ocular motor symptoms in concussed adolescents are linked to retrosplenial activation.

Anna Manelis, João Paulo Lima Santos, Stephen J Suss, Cynthia L Holland, Richelle S Stiffler, Hannah B Bitzer, Sarrah Mailliard, Madelyn A Shaffer, Kaitlin Caviston, Michael W Collins and 3 more

Open access · goldAbstract read
In one paragraph

Article in Brain communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Anna ManelisDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.ORCID https://orcid.org/0000-0002-6605-5130
João Paulo Lima SantosDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.
Stephen J SussDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.
Cynthia L HollandDepartment of Orthopaedic Surgery/UPMC Sports Medicine Concussion Program, University of Pittsburgh, Pittsburgh, PA, USA.
Richelle S StifflerDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.
Hannah B BitzerDepartment of Orthopaedic Surgery/UPMC Sports Medicine Concussion Program, University of Pittsburgh, Pittsburgh, PA, USA.
Sarrah MailliardDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.
Madelyn A ShafferDepartment of Orthopaedic Surgery/UPMC Sports Medicine Concussion Program, University of Pittsburgh, Pittsburgh, PA, USA.
Kaitlin CavistonDepartment of Orthopaedic Surgery/UPMC Sports Medicine Concussion Program, University of Pittsburgh, Pittsburgh, PA, USA.
Michael W CollinsDepartment of Orthopaedic Surgery/UPMC Sports Medicine Concussion Program, University of Pittsburgh, Pittsburgh, PA, USA.
Mary L PhillipsDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.
Anthony P KontosDepartment of Orthopaedic Surgery/UPMC Sports Medicine Concussion Program, University of Pittsburgh, Pittsburgh, PA, USA.
Amelia VersaceDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.ORCID https://orcid.org/0000-0001-9925-5203
University of Pittsburgh · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Following concussion, adolescents often experience vestibular and ocular motor symptoms as well as working memory deficits that may affect their cognitive, academic and social well-being. Complex visual environments including school activities, playing sports, or socializing with friends may be overwhelming for concussed adolescents suffering from headache, dizziness, nausea and fogginess, thus imposing heightened requirements on working memory to adequately function in such environments. While understanding the relationship between working memory and vestibular/ocular motor symptoms is critically important, no previous study has examined how an increase in working memory task difficulty affects the relationship between severity of vestibular/ocular motor symptoms and brain and behavioural responses in a working memory task. To address this question, we examined 80 adolescents (53 concussed, 27 non-concussed) using functional MRI while performing a 1-back (easy) and 2-back (difficult) working memory tasks with angry, happy, neutral and sad face distractors. Concussed adolescents completed the vestibular/ocular motor screening and were scanned within 10 days of injury. We found that all participants showed lower accuracy and slower reaction time on difficult (2-back) versus easy (1-back) tasks (

Indexed as

adolescentsconcussionretrosplenial cortexvestibular/ocular motor symptomsworking memory

Identifiers

PMID35615112
PMCPMC9127539
OpenAlexW4280516252

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.