Evidence map›Paper›PMID 35615042›Full record

ArticleFrontiers in public health2022

Classifying Characteristics of Opioid Use Disorder From Hospital Discharge Summaries Using Natural Language Processing.

Melissa N Poulsen, Philip J Freda, Vanessa Troiani, Anahita Davoudi, Danielle L Mowery

Abstract read
In one paragraph

Article in Frontiers in public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  10. Detecting Opioid Use Disorder in Health Claims Data With Positive Unlabeled Learning.IEEE journal of biomedical and health informatics · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Melissa N PoulsenDepartment of Population Health Sciences, Geisinger, Danville, PA, United States.
Philip J FredaDepartment of Biostatistics, Epidemiology and Informatics, University of Pennsylvania, Philadelphia, PA, United States.
Vanessa TroianiAutism and Developmental Medicine Institute, Geisinger, Danville, PA, United States.
Anahita DavoudiDepartment of Biostatistics, Epidemiology and Informatics, University of Pennsylvania, Philadelphia, PA, United States.
Danielle L MoweryDepartment of Biostatistics, Epidemiology and Informatics, University of Pennsylvania, Philadelphia, PA, United States.

Funding

Supplemental Application for Clinical and Genetic Risk Profile of Opioid Use DisorderR01DA044015 · NIDA · GEISINGER CLINIC · PI BERRETTINI, WADE H, ROBISHAW, JANET D · 2017 to 2021
$4.5M
Postdoctoral Training Program in Genomic MedicineT32HG009495 · NHGRI · UNIVERSITY OF PENNSYLVANIA · PI Katherine L. Nathanson, Bogdan Pasaniuc · 2017 to 2026
$4.2M
Understanding the role of community determinants in opioid use disorder and program implementation factors influencing patient adherence to opioid agonist therapyK01DA049903 · NIDA · GEISINGER CLINIC · PI POULSEN, MELISSA · 2020 to 2024
$810k
NHGRI NIH HHS T32 HG009495NIDA NIH HHS K01 DA049903NIDA NIH HHS R01 DA044015
6 · The paper itself

Abstract

Background: Opioid use disorder (OUD) is underdiagnosed in health system settings, limiting research on OUD using electronic health records (EHRs). Medical encounter notes can enrich structured EHR data with documented signs and symptoms of OUD and social risks and behaviors. To capture this information at scale, natural language processing (NLP) tools must be developed and evaluated. We developed and applied an annotation schema to deeply characterize OUD and related clinical, behavioral, and environmental factors, and automated the annotation schema using machine learning and deep learning-based approaches. Methods: Using the MIMIC-III Critical Care Database, we queried hospital discharge summaries of patients with Results: The resulting annotation schema contained 32 classes. We achieved moderate inter-annotator agreement, with F Conclusion: This pilot study demonstrated that rich information regarding problematic opioid use can be manually identified by annotators. However, more training samples and features would improve our ability to reliably identify less common classes from clinical text, including text from outpatient settings.

Indexed as

Natural Language ProcessingOpioid-Related DisordersAnalgesics, OpioidHospitalsHumansPatient DischargePilot ProjectsAnalgesics, Opioiddeep learningmachine learningnatural language processingopioid-related disorderssubstance usesupervised learning

Identifiers

PMID35615042
PMCPMC9124945

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.