Evidence map›Paper›PMID 35615013›Full record

Trial reportBioMed research international2022

Usefulness of Continuous Low-Dose Fentanyl in Combination with Dexmedetomidine and Midazolam for Intravenous Sedation: A Randomised Controlled Trial.

Yoko Okumura, Aiji Sato Boku, Naoko Tachi, Mayuko Kanazawa, Miko Kawabata, Masahiro Okuda

Open access · hybridAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BioMed research international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Yoko OkumuraDepartment of Anesthesiology, School of Dentistry, Aichi Gakuin University, 2-11 Suemori-Dori, Nagoya, Aichi 464-8651, Japan.ORCID https://orcid.org/0000-0003-2420-2662
Aiji Sato BokuDepartment of Anesthesiology, School of Dentistry, Aichi Gakuin University, 2-11 Suemori-Dori, Nagoya, Aichi 464-8651, Japan.ORCID https://orcid.org/0000-0003-0182-2543
Naoko TachiDepartment of Anesthesiology, School of Dentistry, Aichi Gakuin University, 2-11 Suemori-Dori, Nagoya, Aichi 464-8651, Japan.ORCID https://orcid.org/0000-0002-0439-4874
Mayuko KanazawaDepartment of Anesthesiology, School of Dentistry, Aichi Gakuin University, 2-11 Suemori-Dori, Nagoya, Aichi 464-8651, Japan.
Miko KawabataDepartment of Anesthesiology, School of Dentistry, Aichi Gakuin University, 2-11 Suemori-Dori, Nagoya, Aichi 464-8651, Japan.ORCID https://orcid.org/0000-0001-5717-3971
Masahiro OkudaDepartment of Anesthesiology, School of Dentistry, Aichi Gakuin University, 2-11 Suemori-Dori, Nagoya, Aichi 464-8651, Japan.ORCID https://orcid.org/0000-0001-5655-457X
Aichi Gakuin University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intravenous dexmedetomidine (DEX) and midazolam (MZ) are currently used to achieve sedation in dental surgery under local anaesthesia. However, the efficacy of low-dose fentanyl (FEN) in combination with DEX and MZ sedation remains unclear. Therefore, we implemented a prospective randomised controlled trial to investigate the intra- and postoperative analgesic effects, intraoperative respiratory and circulatory dynamics, and frequency of intra- and postoperative adverse events of continuous low-dose fentanyl administration with DEX and MZ sedation. Patients aged 20-64 years scheduled for dental surgery under sedation were randomly assigned to the DEX+MZ (DM) or DEX+MZ+FEN (DMF) group. DEX was administered at 4

Indexed as

AnesthesiaDexmedetomidineFentanylHumansHypnotics and SedativesMidazolamProspective StudiesDexmedetomidineFentanylHypnotics and SedativesMidazolam

Identifiers

PMID35615013
PMCPMC9126687
OpenAlexW4280587118

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.