Evidence map›Paper›PMID 35614935›Full record

ReviewFrontiers in pharmacology2022

Research Progress of RNA Methylation Modification in Colorectal Cancer.

Weizheng Liang, Hongyang Yi, Chenyu Mao, Qingxue Meng, Xueliang Wu, Shanliang Li, Jun Xue

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Weizheng LiangCentral Laboratory, The First Affiliated Hospital of Hebei North University, Zhangjiakou, China.
Hongyang YiThe Third People's Hospital of Shenzhen, Shenzhen, China.
Chenyu MaoSchool of Engineering and Applied Science, University of Pennsylvania, Philadelphia, PA, United States.
Qingxue MengCentral Laboratory, The First Affiliated Hospital of Hebei North University, Zhangjiakou, China.
Xueliang WuDepartment of General Surgery, The First Affiliated Hospital of Hebei North University, Zhangjiakou, China.
Shanliang LiDepartment of Pharmacology, Guangxi University of Chinese Medicine, Nanning, China.
Jun XueDepartment of General Surgery, The First Affiliated Hospital of Hebei North University, Zhangjiakou, China.
Hebei North University · CNGuangxi University of Chinese Medicine · CNShenzhen Third People’s Hospital · CNUniversity of Pennsylvania · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Accumulating evidence indicates that RNA methylation, as the most common modification of mRNA, is of great significance in tumor progression and metastasis. Colorectal cancer is a common malignant tumor of the digestive system that seriously affects the health of middle-aged and elderly people. Although there have been many studies on the biological mechanism of the occurrence and development of colorectal cancer, there are still major deficiencies in the diagnosis and prognosis of colorectal cancer. With the deep study of RNA methylation, it was found that RNA modification is highly related to colorectal cancer tumorigenesis, development and prognosis. Here, we will highlight various RNA chemical modifications including N6-methyladenosine, 5-methylcytosine, N1-methyladenosine, 7-methylguanine, pseudouridine and their modification enzymes followed by summarizing their functions in colorectal cancer.

Indexed as

5-methylcytosine7-methylguaninecircular RNAcolorectal cancerN1-methyladenosineN6-methyladenosineRNA methylationRNA modification

Identifiers

PMID35614935
PMCPMC9125385
OpenAlexW4225426354

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.