Evidence map›Paper›PMID 35614571›Full record

ArticlePediatric blood & cancer2022

Mental health assessment of youth with sickle cell disease and their primary caregivers during the COVID-19 pandemic.

Nancy S Green, Deepa Manwani, Kim Smith-Whitley, Banu Aygun, Abena Appiah-Kubi, Arlene M Smaldone

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Pediatric blood & cancer, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03462511 (Hydroxyurea Adherence for Personal Best in Sickle Cell Disease), which is not on this map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03462511 nacompletednot on this map

Hydroxyurea Adherence for Personal Best in Sickle Cell Disease (HABIT): Efficacy Trial

TypeinterventionalSponsorColumbia UniversityRan2018 to 2021Enrolled50ConditionsSickle Cell DiseaseArmsHABIT Intervention, Standard of Care, Education materials
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Nancy S GreenDivision of Hematology, Oncology and Stem Cell Transplantation, Department of Pediatrics, Columbia University Irving Medical Center, New York, New York, USA.ORCID 0000-0002-9877-1561
Deepa ManwaniDivision of Hematology and Oncology, Department of Pediatrics, Albert Einstein College of Medicine, New York, New York, USA.ORCID 0000-0003-1057-1811
Kim Smith-WhitleyDivision of Hematology and Oncology and Stem cell transplantation, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.ORCID 0000-0002-2790-411X
Banu AygunDivision of Hematology and Oncology and Cellular Therapy, Cohen Children's Medical Center, New Hyde Park, New York, USA.ORCID 0000-0001-9934-5161
Abena Appiah-KubiDivision of Hematology and Oncology and Cellular Therapy, Cohen Children's Medical Center, New Hyde Park, New York, USA.ORCID 0000-0001-8147-3624
Arlene M SmaldoneSchool of Nursing and College of Dental Medicine, Columbia University Irving Medical Center, New York, New York, USA.ORCID 0000-0001-8326-5036
Cohen Children's Medical Center · USColumbia University Irving Medical Center · USAlbert Einstein College of Medicine · USChildren's Hospital of Philadelphia · US

Funding

Reaching Communities through the Design of Information Visualizations (ReDIVis) Toolbox to Address COVID-19 Vaccine Hesitancy and Uptake.P30NR016587 · NINR · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI BAKKEN, SUZANNE, SMALDONE, ARLENE M · 2016 to 2022
$4.3M
Hydroxyurea Adherence for Personal Best in Sickle Cell Treatment: HABITR01NR017206 · NINR · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GREEN, NANCY S., SMALDONE, ARLENE M · 2017 to 2020
$2.9M
NINR NIH HHS P30 NR016587NINR NIH HHS R01 NR017206
6 · The paper itself

Abstract

Youth with sickle cell disease (SCD) and their caregivers are susceptible to stress and depression, perhaps exacerbated by pandemic-associated health and economic concerns. Most of the 50 youth-caregiver dyads enrolled in the multisite trial, Hydroxyurea Adherence for Personal Best in Sickle Cell Treatment (HABIT), took an online survey of self-reported mental health symptoms and food insecurity during the 2020 COVID-19 pandemic. Compared to largely pre-pandemic results, prevalence of mental health symptoms in dyad members appeared to have shifted: fewer youth and more caregivers were affected during the pandemic; many of both groups lacked optimism. Pandemic/post-pandemic screening of youth with SCD for mental health symptoms and food insecurity appears warranted.

Indexed as

Anemia, Sickle CellCOVID-19AdolescentCaregiversDepressionHumansMental HealthPandemicsanxietydepressionmental healthpandemicsickle cell diseaseyouth

Identifiers

PMID35614571
PMCPMC9348143
OpenAlexW4281572734

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.