ArticleEndocrinology, diabetes & metabolism2022
Comparison between D-dimer levels in diabetic and non-diabetic positive COVID-19 adult patients: A hospital-based study.
Article in Endocrinology, diabetes & metabolism, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed, 7 citations in OpenAlex.
- Risk correlation analysis of serum adiponectin (APN), D-dimer (DD) and the neutrophil - lymphocyte ratio (NLR) with the prognosis of diabetic foot ulcer infection.Journal of medical biochemistry · 2026Article
- Factors Affecting the Outcomes of COVID-19 in Diabetes Patients at Haji Adam Malik General Hospital Medan, Indonesia.Acta informatica medica : AIM : journal of the Society for Medical Informatics of Bosnia & Herzegovina : casopis Drustva za medicinsku informatiku BiH · 2023Article
- Comparison between D-dimer levels in diabetic and non-diabetic positive COVID-19 adult patients: A hospital-based study.Endocrinology, diabetes & metabolism · 2022Article
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
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Abstract
backgroundDiabetes is one of the most common associated comorbidity with severe acute respiratory syndrome coronavirus (SARS-CoV-2) pneumonia patients. Coagulation disorders with D-dimer levels are increased in both diseases. This study aimed to compare the levels of D-dimer in DM and non-DM patients with coronavirus disease (COVID-19) and correlate it with the disease severity.
methodsThis is a cross-sectional hospital-based study. It was conducted at royal care hospital, isolation COVID-19 Centre in 2021. The study included 130 patients with COVID-19 who fulfilled the inclusion criteria. Data were collected through a structured datasheet. The disease was diagnosed by a nasal swab polymerase chain reaction (PCR) Participants were divided into diabetics and non-diabetics depending on the history from the datasheet. The data were analysed with Statistical Package of Social Science (SPSS) version 23.
resultsThe study showed that 73.1% of the participants were males and 26.9% were females. The most frequent age group was >65 years. The percentages of diabetics and non-diabetics, among the study participants, were found to be 41.5% and 58.5%, respectively. Moreover, 52.3% were admitted to the intensive care unit (ICU). This study revealed that D-dimer was higher compared with diabetes mellitus. The diabetics were associated with higher levels of D-dimer compared to non-diabetics. Regarding the correlation between the level of D-dimer and severity of COVID-19, it was found that there is a significant association, as the ICU patients were associated with higher levels of D-dimer in comparison with non-ICU patients.
conclusionThis study concluded that there is a significant association between the high D-dimer level and severity of COVID-19 among diabetic patients.
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