ArticlePediatric pulmonology2022
Poor early childhood growth is associated with impaired lung function: Evidence from a Ghanaian pregnancy cohort.
Article in Pediatric pulmonology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
8 citing papers in PubMed, 12 citations in OpenAlex.
- Household Air Pollution and Child Lung Function: The Ghana Randomized Air Pollution and Health Study.American journal of respiratory and critical care medicine · 2024Trial
- Prenatal Household Air Pollution Exposure and Childhood Blood Pressure in Rural Ghana.Environmental health perspectives · 2024Trial
- Prenatal and child malaria and child growth: evidence from a Ghanaian pregnancy cohort.BMJ paediatrics open · 2026Article
- Prenatal and postnatal household air pollution and longitudinal growth trajectories: results from long-term follow up of the GRAPHS cohort.Environment international · 2026Article
- Anthropometric growth trajectories of children presenting with presumptive pulmonary TB.IJTLD open · 2025Article
- Respiratory rates among rural Gambian children: a community-based cohort study.Scientific reports · 2024Article
- Geospatial determinants of maternal and child exposure to fine particulate matter in Kintampo, Ghana: Levels within the household and community, by surrounding building density and near roadways.Journal of exposure science & environmental epidemiology · 2024Article
- Preterm birth, birth weight, infant weight gain and their associations with childhood asthma and spirometry: a cross-sectional observational study in Nairobi, Kenya.BMJ open respiratory research · 2023Observational
Corrections and comments
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Authors and funding
16 authors at 6 institutions in 2 countries.
Funding
Abstract
objectivesNearly 40% of African children under 5 are stunted. We leveraged the Ghana randomized air pollution and health study (GRAPHS) cohort to examine whether poorer growth was associated with worse childhood lung function. STUDY
designGRAPHS measured infant weight and length at birth and 3, 6, 9,12 months, and 4 years of age. At age 4 years, n = 567 children performed impulse oscillometry. We employed multivariable linear regression to estimate associations between birth and age 4 years anthropometry and lung function. Next, we employed latent class growth analysis (LCGA) to generate growth trajectories through age 4 years. We employed linear regression to examine associations between growth trajectory assignment and lung function.
resultsBirth weight and age 4 weight-for-age and height-for-age z-scores were inversely associated with airway resistance (e.g., R
conclusionChildren with poorer anthropometrics through to age 4 years had higher airway resistance in early childhood. These findings have implications for lifelong lung health, including pneumonia risk in childhood and reduced maximally attainable lung function in adulthood.
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Registered trials
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