Evidence map›Paper›PMID 35614356›Full record

ArticleEnvironmental science and pollution research international2022

Amelioration of aluminum-induced hepatic and nephrotoxicity by Premna odorata extract is mediated by lowering MMP9 and TGF-β gene alterations in Wistar rat.

Walaa M S Ahmed, Marwa A Ibrahim, Nermeen A Helmy, Akram M ElKashlan, Abeer H Elmaidomy, Amr R Zaki

Open access · hybridAbstract read
In one paragraph

Article in Environmental science and pollution research international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
4.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 23 citations in OpenAlex.

  1. Assessment of ion release, cytotoxicity, and potential systemic toxicity of titanium dental alloy.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026
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  5. Article
  6. AlClFrontiers in toxicology · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Plants (Basel, Switzerland) · 2023
    Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Walaa M S AhmedDepartment of Clinical Pathology, Faculty of Veterinary Medicine, Beni-Suef University, Beni-Suef, Egypt.
Marwa A IbrahimDepartment of Biochemistry and Molecular Biology, Faculty of Veterinary Medicine, Cairo University, Giza, Egypt. marwaibrahim@cu.edu.eg.
Nermeen A HelmyDepartment of Physiology, Faculty of Veterinary Medicine, Beni-Suef University, Beni-Suef, Egypt.
Akram M ElKashlanDepartment of Biochemistry, Faculty of Pharmacy, University of Sadat City, Sadat City, Egypt.
Abeer H ElmaidomyDepartment of Pharmacognosy, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt.
Amr R ZakiDepartment of Forensic Medicine and Clinical Toxicology, Faculty of Medicine, Beni-Suef University, Beni-Suef, Egypt.
Beni-Suef University · EGCairo University · EGUniversity of Sadat City · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aims to investigate the effect of Premna odorata (P. odorata) (Lamiaceae) on the hepatic and nephrotoxicity induced by aluminum chloride (AlCl

Indexed as

AntioxidantsLamiaceaeAlanine TransaminaseAlbuminsAlkaline PhosphataseAluminumAluminum ChlorideAnimalsAspartate AminotransferasesBiomarkersCatalaseCholesterolCreatinineGlutathioneLiverMaleAlanine TransaminaseAlbuminsAlkaline PhosphataseAluminumAluminum ChlorideAntioxidantsAspartate AminotransferasesBiomarkersCatalaseCholesterolCreatinineGlutathioneMalondialdehydeMatrix Metalloproteinase 9OxidantsRNA, MessengerTransforming Growth Factor betaTransforming Growth FactorsTriglyceridesTumor Necrosis Factor-alphaUreaAluminum toxicityFamily LamiaceaeKidneyLiverMMP9 genePremna odorataTGF-β gene

Identifiers

PMID35614356
PMCPMC9522688
OpenAlexW4281551476

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.