Evidence map›Paper›PMID 35614328›Full record

ReviewVirus genes2022

Non-structural proteins of bovine viral diarrhea virus.

Shanshan Chi, Si Chen, Weijuan Jia, Yunjiang He, Linzhu Ren, Xueli Wang

Open access · greenAbstract readReview
In one paragraph

Review in Virus genes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
11.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 53 citations in OpenAlex.

  1. Article
  2. Article
  3. Characterization ofViruses · 2026
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  5. Review
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  16. Review
  17. Review
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  19. Molecular characteristics of a potentially novel BVDV (Frontiers in veterinary science · 2025
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Shanshan Chi *College of Animal Science and Technology, Inner Mongolia Minzu University, Tongliao, 028000, China.ORCID http://orcid.org/0000-0002-2194-7207
Si Chen *College of Animal Sciences, Key Lab for Zoonoses Research, Ministry of Education, Jilin University, Changchun, 130062, China.
Weijuan JiaCollege of Animal Science and Technology, Inner Mongolia Minzu University, Tongliao, 028000, China.
Yunjiang HeCollege of Animal Science and Technology, Inner Mongolia Minzu University, Tongliao, 028000, China.
Linzhu RenCollege of Animal Sciences, Key Lab for Zoonoses Research, Ministry of Education, Jilin University, Changchun, 130062, China. renlz@jlu.edu.cn.
Xueli WangCollege of Animal Science and Technology, Inner Mongolia Minzu University, Tongliao, 028000, China. wangxl9577@aliyun.com.
Minzu University of China · CNJilin University · CNInner Mongolia University for Nationalities · CN

Funding

Inner Mongolia Natural Science FoundationInner Mongolia Natural Science Foundation 2021LHMS03008
6 · The paper itself

Abstract

Bovine viral diarrhea virus (BVDV) belongs to the family Flaviviridae genus pestivirus. The viral genome is a single-stranded, positive-sense RNA that encodes four structural proteins (i.e., C, Erns, E1, and E2) and eight non-structural proteins (NSPs) (i.e., Npro, p7, NS2, NS3, NS4A, NS4B, NS5A, and NS5B). Cattle infected with BVDV exhibit a number of different clinical signs including diarrhea, abortion, and other reproductive disorders which have a serious impact on the cattle industry worldwide. Research on BVDV mainly focuses on its structural protein, however, progress in understanding the functions of the NSPs of BVDV has also been made in recent decades. The knowledge gained on the BVDV non-structural proteins is helpful to more fully understand the viral replication process and the molecular mechanism of viral persistent infection. This review focuses on the functions of BVDV NSPs and provides references for the identification of BVDV, the diagnosis and prevention of Bovine viral diarrhea mucosal disease (BVD-MD), and the development of vaccines.

Indexed as

Bovine Virus Diarrhea-Mucosal DiseaseDiarrhea Virus 1, Bovine ViralDiarrhea Viruses, Bovine ViralAnimalsCattleCell LineDiarrheaRNA, ViralViral Nonstructural ProteinsRNA, ViralViral Nonstructural ProteinsBovine viral diarrhea virus (BVDV)FunctionsNonstructural proteins (NSPs)Vaccine

Identifiers

PMID35614328
PMCPMC9131992
OpenAlexW4281477291

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.