Evidence map›Paper›PMID 35614288›Full record

ArticleBehavior genetics2022

LGBTQ+ Perspectives on Conducting Genomic Research on Sexual Orientation and Gender Identity.

Catherine Hammack-Aviran, Ayden Eilmus, Carolyn Diehl, Keanan Gabriel Gottlieb, Gilbert Gonzales, Lea K Davis, Ellen Wright Clayton

Abstract read
In one paragraph

Article in Behavior genetics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Catherine Hammack-AviranCenter for Biomedical Ethics and Society, Vanderbilt University Medical Center, 2525 West End Ave., Suite 400, Nashville, TN, 37203, USA.
Ayden EilmusCollege of Arts and Sciences, Vanderbilt University, Nashville, TN, USA.
Carolyn DiehlCenter for Biomedical Ethics and Society, Vanderbilt University Medical Center, 2525 West End Ave., Suite 400, Nashville, TN, 37203, USA.
Keanan Gabriel GottliebProgram for LGBTQ Health, Vanderbilt University Medical Center, Nashville, TN, USA.
Gilbert GonzalesVanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA.
Lea K DavisDepartment of Medicine, Health and Society, Vanderbilt University, Nashville, TN, USA.
Ellen Wright ClaytonCenter for Biomedical Ethics and Society, Vanderbilt University Medical Center, 2525 West End Ave., Suite 400, Nashville, TN, 37203, USA. Ellen.clayton@vumc.org.ORCID http://orcid.org/0000-0002-0308-4110

Funding

Genetic Privacy and Identity in Community Settings - GetPreCiSeRM1HG009034 · NHGRI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI CLAYTON, ELLEN WRIGHT, MALIN, BRADLEY A. · 2016 to 2024
$8.3M
Genetic Privacy and Identity in Sexual and Gender Minorities: GetPrISMR21HG010652 · NHGRI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI CLAYTON, ELLEN WRIGHT · 2019 to 2020
$468k
NHGRI NIH HHS R21 HG010652NHGRI NIH HHS RM1 HG009034
6 · The paper itself

Abstract

We conducted in-depth, semi-structured interviews with LGBTQ+-identified individuals (n = 31) to explore the range of LGBTQ+ perspectives on genomic research using either sexual orientation or gender identity (SOGI) data. Most interviewees presumed that research would confirm genetic contributions to sexual orientation and gender identity. Primary hopes for such confirmation included validating LGBTQ+ identities, improved access to and quality of healthcare and other resources, and increased acceptance in familial, socio-cultural, and political environments. Areas of concern included threats of pathologizing and medicalizing LGBTQ+ identities and experiences, undermining reproductive rights, gatekeeping of health or social systems, and malicious testing or misuse of genetic results, particularly for LGBTQ+ youth. Overall, interviewees were divided on the acceptability of genomic research investigating genetic contributions to sexual orientation and gender identity. Participants emphasized researchers' ethical obligations to LGBTQ+ individuals and endorsed engagement with LGBTQ+ communities throughout all aspects of genomic research using SOGI data.

Indexed as

Gender IdentitySexual and Gender MinoritiesAdolescentFemaleGenomicsHumansMaleSexual BehaviorAttitudes about genomics researchLGBTQ+ healthQualitative researchSexual orientation and gender identity

Identifiers

PMID35614288
PMCPMC9132750

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.