Evidence map›Paper›PMID 35614253›Full record

ArticleArchives of dermatological research2023

Investigating the epidemiological relationship between vitiligo and psoriasis: a population-based study.

Khalaf Kridin, Keren Lyakhovitsky, Erez Onn, Anna Lyakhovitsky, Ralf Ludwig, Orly Weinstein, Arnon D Cohen

Abstract read
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In one paragraph

Article in Archives of dermatological research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
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  5. Article
  6. The relationship between psoriasis and vitiligo: From a comprehensive study.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Khalaf Kridin *Unit of Dermatology and Skin Research Laboratory, Baruch Padeh Poria Medical Center, M.P. The lower Galilee, 15208, Poriya, Israel. dr_kridin@hotmail.com.ORCID http://orcid.org/0000-0001-9971-9151
Keren Lyakhovitsky *Azrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel.
Erez OnnBaruch Padeh Medical Center, Poriya, Israel.
Anna LyakhovitskyDepartment of Dermatology, Sheba Medical Center, Tel-Hashomer, Ramat-Gan, Israel.
Ralf LudwigLübeck Institute of Experimental Dermatology, University of Lübeck, Lübeck, Germany.
Orly Weinstein *Clalit Health Services, Tel-Aviv, Israel.
Arnon D Cohen *Clalit Health Services, Tel-Aviv, Israel.
Bar-Ilan University · ILBen-Gurion University of the Negev · ILPoriya Medical Center · ILTel Aviv University · ILUniversity of Lübeck · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe association of vitiligo with psoriasis is inconsistent in the current literature.

objectiveTo assess the bidirectional association between vitiligo and psoriasis.

methodsA population-based study was performed to compare vitiligo patients (n = 20,851) with age-, sex- and ethnicity-matched control subjects (n = 102,475) regarding the incidence of new-onset and the prevalence of preexisting psoriasis. Adjusted hazard ratios (HRs) and adjusted odds ratios (ORs) were calculated by cox regression and logistic regression, respectively.

resultsThe incidence rate of new-onset psoriasis was estimated at 7.9 (95% CI 6.4-9.7) and 4.7 (95% CI 4.1-5.3) cases per 10,000 person-years among patients with vitiligo and controls, respectively. Patients with vitiligo experienced an increased risk of psoriasis (fully-adjusted HR 1.71; 95% CI 1.35-2.17; P < 0.001). On the other hand, the odds of vitiligo were only marginally elevated among patients with preexisting psoriasis (fully-adjusted OR 1.19; 95% CI 1.01-1.40; P = 0.051). Compared to other patients with vitiligo, those with vitiligo and comorbid psoriasis were older at the onset of the disease and had a greater prevalence of metabolic and cardiovascular comorbidities.

conclusionsA diagnosis of vitiligo predisposes individuals to develop subsequent psoriasis. Clinicians managing dermatologic patients ought to be aware of this comorbidity. Further research is required to explicate the pathomechanism underlying this epidemiological observation.

Indexed as

PsoriasisVitiligoComorbidityHumansIncidencePrevalenceRisk FactorsComorbidityEpidemiologyPsoriasisVitiligo

Identifiers

PMID35614253
OpenAlexW4281482076

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.