ArticleCommunications biology2022
Amplification of cell signaling and disease resistance by an immunity receptor Ve1Ve2 heterocomplex in plants.
Article in Communications biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- The C-terminal tail of Cf resistance proteins determines the intensity of the effector-triggered hypersensitive response-related cell death.Plant physiology · 2026Article
- Advances in CRISPR Plant Applications.International journal of molecular sciences · 2026Review
- Verticillium dahliae Secretory Aspartyl Protease VdSAP Targets Cotton GhARP to Modulate Plant Defence and Defoliation.Molecular plant pathology · 2025Article
- A novel xylanase from a myxobacterium triggers a plant immune response in Nicotiana benthamiana.Molecular plant pathology · 2024Article
- Functional Characterization ofMicrobiology spectrum · 2023Article
- Tissues and mechanisms associated with Verticillium wilt resistance in tomato using bi-grafted near-isogenic lines.Journal of experimental botany · 2023Article
- RNA Interference Past and Future Applications in Plants.International journal of molecular sciences · 2023Review
- Amino acid motifs for the identification of novel protein interactants.Computational and structural biotechnology journal · 2023Review
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Immunity cell-surface receptors Ve1 and Ve2 protect against fungi of the genus Verticillium causing early dying, a worldwide disease in many crops. Characterization of microbe-associated molecular pattern immunity receptors has advanced our understanding of disease resistance but signal amplification remains elusive. Here, we report that transgenic plants expressing Ve1 and Ve2 together, reduced pathogen titres by a further 90% compared to plants expressing only Ve1 or Ve2. Confocal and immunoprecipitation confirm that the two receptors associate to form heteromeric complexes in the absence of the ligand and positively regulate signaling. Bioassays show that the Ve1Ve2 complex activates race-specific amplified immunity to the pathogen through a rapid burst of reactive oxygen species (ROS). These results indicate a mechanism by which the composition of a cell-surface receptor heterocomplex may be optimized to increase immunity against devastating plant diseases.
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